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Methods in Molecular Biology

Pain Research

Methods and Protocols

Editors: Luo, Z. David (Ed.)

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $139.00
price for USA (gross)
  • ISBN 978-1-61779-561-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.00
price for USA
  • ISBN 978-1-61779-560-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.00
price for USA
  • ISBN 978-1-4939-6095-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The advancements of medical technology, improvements in medical care, and increased patients’ life span make pain research and related drug development high priorities for both the research community and pharmaceutical companies. Rapid development of basic science research tools, such as techniques of flurometric labeling, genomic and proteomic high throughput screening, and genetically modified animals, promotes the swift acceleration of pain research to a stage allowing integrated investigations of pain processing mechanisms at the single cell and/or molecule level, and in a spatially and temporally controlled manner.  Using multidisciplinary approaches, we can dissect the complicity of the sensory circuits connecting peripheral stimulation to maladaptive changes in the sensory pathways as well as pain perceptions at the central nervous system. Pain Research: Methods and Protocols, Second Edition provides advanced techniques and animal models that are critical for integrated pain research. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.

 

Authoritative and accessible, Pain Research: Methods and Protocols, Second Edition serves as an ideal guide to novice pain researchers who may not have extensive experiences in the field, or to experienced pain researchers who would like to expand their research in new directions and/or to new mechanisms in different models. 

Reviews

From the reviews of the second edition:

“This second edition of Pain Research – Methods and Protocols is an excellent compendium of chapters outlining the most current techniques used to study the neurobiology of pain. … Pain Research – Methods and Protocols is aimed not only at the novice researcher with little experience in the field but also at bringing new techniques and approaches to the pain research community as a whole. The clear organizational structure of the text makes this a highly achievable goal.” (Bradley Kerr, Canadian Journal of Anesthesia/Journal Canadien d'anesthésie, Vol. 60, January, 2013)

Table of contents (21 chapters)

  • Advancements in Pain Research

    Luo, Z. David

    Pages 1-8

  • Genomic Methods for Clinical and Translational Pain Research

    Wang, Dan (et al.)

    Pages 9-46

  • Two-Dimensional Gel Electrophoresis: Discovering Neuropathic Pain-Associated Synaptic Biomarkers in Spinal Cord Dorsal Horn

    Singh, Om V. (et al.)

    Pages 47-63

  • Whole-Cell Patch-Clamp Recordings on Spinal Cord Slices

    Deng, Ping (et al.)

    Pages 65-72

  • Whole-Cell Recording in Isolated Primary Sensory Neurons

    Gold, Michael S.

    Pages 73-97

Buy this book

eBook $139.00
price for USA (gross)
  • ISBN 978-1-61779-561-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.00
price for USA
  • ISBN 978-1-61779-560-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.00
price for USA
  • ISBN 978-1-4939-6095-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Pain Research
Book Subtitle
Methods and Protocols
Editors
  • Z. David Luo
Series Title
Methods in Molecular Biology
Series Volume
851
Copyright
2012
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-61779-561-9
DOI
10.1007/978-1-61779-561-9
Hardcover ISBN
978-1-61779-560-2
Softcover ISBN
978-1-4939-6095-8
Series ISSN
1064-3745
Edition Number
2
Number of Pages
XI, 287
Number of Illustrations and Tables
63 b/w illustrations, 3 illustrations in colour
Topics