Neuromethods

Animal Models of Movement Disorders

Volume I

Editors: Lane, Emma L., Dunnett, Stephen B. (Eds.)

  • Serves as a comprehensive and valuable reference for those studying motor disorders
  • Provides appropriate models and assessment tools
  • Includes clear, easy to follow methods with expert implemenation advice
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eBook $129.00
price for USA (gross)
  • ISBN 978-1-61779-298-4
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Hardcover $169.00
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  • ISBN 978-1-61779-297-7
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About this book

Movement is the way that animals interact with their environment and is under the organization and complex control of the brain and spinal cord. Multiple central nervous systems, including cortex, basal ganglia, cerebellum, and brainstem, interact to provide precise motor control and integration. Damage or disease within these systems cause profound motor disturbances in man, which can be effectively modeled in animals to develop a better understanding and treatment of the human condition. Animal Models of Movement Disorders introduces a variety of methods and techniques used to model and assess motor function in experimental animals from lower orders, such as drosophila and c. elegans, through vertebrate species including fish, to mammals, such as rodents and non-human primates. The most advanced contemporary models in each system are presented at multiple levels of analysis from molecular and genetic modeling, lesions, anatomy, neurochemistry, to imaging and behavior. Volume I contains general methods of movement disorder assessment as well as an extensive section on dopamine systems. 

 

Comprehensive and meticulous, Animal Models of Movement Disorders serves as a valuable reference for those studying motor disorders by covering methodologies in detail and providing the information necessary to consider both the appropriate models and assessment tools that can most informatively answer the key experimental issues in the field.

Table of contents (21 chapters)

  • Why Cannot a Rodent Be More Like a Man? A Clinical Perspective

    Rosser, Anne E.

    Pages 3-9

  • Zebrafish as a Vertebrate Model Organism for Studying Movement Disorders

    Sundvik, Maria (et al.)

    Pages 11-30

  • Methodological Strategies to Evaluate Functional Effectors Related to Parkinson’s Disease Through Application of Caenorhabditis elegans Models

    Caldwell, Kim A. (et al.)

    Pages 31-53

  • Effects of Alpha-Synuclein Expression on Behavioral Activity in Drosophila  : A Simple Model of Parkinson’s Disease

    Pendleton, Robert G. (et al.)

    Pages 55-63

  • Neurological Evaluation of Movement Disorders in Mice

    Brooks, Simon P.

    Pages 65-86

Buy this book

eBook $129.00
price for USA (gross)
  • ISBN 978-1-61779-298-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.00
price for USA
  • ISBN 978-1-61779-297-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Animal Models of Movement Disorders
Book Subtitle
Volume I
Editors
  • Emma L. Lane
  • Stephen B. Dunnett
Series Title
Neuromethods
Series Volume
61
Copyright
2012
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-61779-298-4
DOI
10.1007/978-1-61779-298-4
Hardcover ISBN
978-1-61779-297-7
Series ISSN
0893-2336
Edition Number
1
Number of Pages
XV, 447
Topics