Methods in Molecular Biology

Molecular Chaperones

Methods and Protocols

Editors: Calderwood, Stuart K., Prince, Thomas L. (Eds.)

  • Approaches the study of heat shock transcription factors both in vivo and in vitro
  • Features step-by-step protocols which are tested and ready for the lab
  • Includes expert tips and vital implementation advice to ensure successful results
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eBook $129.00
price for USA (gross)
  • ISBN 978-1-61779-295-3
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.00
price for USA
  • ISBN 978-1-61779-294-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The proteome consists of a complex mixture of proteins each of which need to be folded correctly in order to function for the health of the organism, and many of these proteins require molecular chaperones to reach the correct conformation and, in some cases, to remain in a folded form.  In Molecular Chaperones: Methods and Protocols, expert researchers address a wide variety of approaches to the study these mechanisms, featuring the workings of heat shock proteins and heat shock transcription factors, in vitro and in vivo. Written in the highly successful Methods in Molecular Biology™ series format, chapters features introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

 

Authoritative and cutting-edge, Molecular Chaperones: Methods and Protocols serves as an ideal guide for all scientists who wish to pursue this vital biological action and its impact on human health and disease.

Reviews

From the reviews:

“This book details current methods and protocols essential for understanding the biological properties and roles of the molecular chaperones … . It appears to be written for all scientists interested in understanding the roles of molecular chaperones, which would include students and researchers interested in heat shock proteins. … This will be a useful guide for all scientists interested in the field of heat shock proteins and molecular chaperones and their role in health and disease.” (Omer Iqbal, Doody’s Book Reviews, December, 2011)

Table of contents (23 chapters)

  • Targeted Deletion of Hsf1, 2, and 4 Genes in Mice

    Jin, Xiongjie (et al.)

    Pages 1-20

  • The Role of Heat Shock Factors in Stress-Induced Transcription

    Zhang, Yue (et al.)

    Pages 21-32

  • Hsp90 and Client Protein Maturation

    Wayne, Natalie (et al.)

    Pages 33-44

  • The Role of p23, Hop, Immunophilins, and Other Co-chaperones in Regulating Hsp90 Function

    Cox, Marc B. (et al.)

    Pages 45-66

  • Detecting HSP90 Phosphorylation

    Mollapour, Mehdi (et al.)

    Pages 67-74

Buy this book

eBook $129.00
price for USA (gross)
  • ISBN 978-1-61779-295-3
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.00
price for USA
  • ISBN 978-1-61779-294-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Molecular Chaperones
Book Subtitle
Methods and Protocols
Editors
  • Stuart K. Calderwood
  • Thomas L. Prince
Series Title
Methods in Molecular Biology
Series Volume
787
Copyright
2011
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-61779-295-3
DOI
10.1007/978-1-61779-295-3
Hardcover ISBN
978-1-61779-294-6
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XVIII, 321
Topics