Methods in Molecular Biology

Protein Microarray for Disease Analysis

Methods and Protocols

Editors: Wu, Catherine J. (Ed.)

  • Serves as a toolkit of methodologies currently used in studying the field of protein microarray
  • Features step-by-step protocols ready for the laboratory
  • Contains expert tips and vital implementation advice to ensure success
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eBook $129.00
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  • ISBN 978-1-61779-043-0
  • Digitally watermarked, DRM-free
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  • Immediate eBook download after purchase
Hardcover $169.00
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  • ISBN 978-1-61779-042-3
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About this book

Protein microarrays have been used for a wide variety of important tasks, such as identifying protein-protein interactions, discovering disease biomarkers, identifying DNA-binding specificity by protein variants, and for characterization of the humoral immune response.  In Protein Microarray for Disease Analysis: Methods and Protocols, expert researchers provide concise descriptions of the methodologies currently used to fabricate microarrays for the comprehensive analysis of proteins or responses to proteins that can be used to dissect human disease.  These methodologies are the toolbox for revolutionizing drug development and cell-level biochemical understanding of human disease processes.  Beginning with a section on protein-detecting analytical microarrays, the volume continues with sections covering antigen microarrays for immunoprofiling, protein function microarrays, the validation of candidate targets, proteomic libraries, as well as signal detection strategies and data analysis techniques.  Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

 

Practical and cutting-edge,  Protein Microarray for Disease Analysis: Methods and Protocols serves as a solid framework to aid scientists in understanding how protein microarray technology is presently developing and how it can be applied to transform our analysis of human disease.

Reviews

From the reviews:

“This is a well-illustrated book with concise descriptions of the methodologies currently used to fabricate microarrays for the comprehensive analysis of proteins or responses to proteins that can be used to detect disease. … The book is intended for scientists, but it also will be of immense help to graduate students and researchers interested protein microarrays. … a well-done resource on the methodologies currently used in protein microarrays to promote a cell-level biochemical understanding of human disease processes that could revolutionize drug development.” (Omer Iqbal, Doody’s Review Services, July, 2011)

Table of contents (22 chapters)

  • Detecting and Quantifying Multiple Proteins in Clinical Samples in High-Throughput Using Antibody Microarrays

    Knickerbocker, Tanya (et al.)

    Pages 3-13

  • Analysis of Serum Protein Glycosylation with Antibody–Lectin Microarray for High-Throughput Biomarker Screening

    Li, Chen (et al.)

    Pages 15-28

  • Antibody Suspension Bead Arrays

    Schwenk, Jochen M. (et al.)

    Pages 29-36

  • Reverse Protein Arrays Applied to Host–Pathogen Interaction Studies

    Cid, Víctor J. (et al.)

    Pages 37-55

  • Identification and Optimization of DNA Aptamer Binding Regions Using DNA Microarrays

    Fischer, Nicholas O. (et al.)

    Pages 57-66

Buy this book

eBook $129.00
price for USA (gross)
  • ISBN 978-1-61779-043-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.00
price for USA
  • ISBN 978-1-61779-042-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Protein Microarray for Disease Analysis
Book Subtitle
Methods and Protocols
Editors
  • Catherine J. Wu
Series Title
Methods in Molecular Biology
Series Volume
723
Copyright
2011
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-61779-043-0
DOI
10.1007/978-1-61779-043-0
Hardcover ISBN
978-1-61779-042-3
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XIII, 373
Topics