Contemporary Neuroscience

Neural Development and Stem Cells

Editors: Lipnick, Scott, Vemuri, Mohan C., Carpenter, Melissa (Eds.)

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About this book

Developing the second edition of Neural Development and Stem Cells was neces- tated by the rapid increase in our knowledge of the development of the nervous system. It has become increasingly clear that stem cells are a heterogeneous population that changes extensively during development. Perhaps the most important advance in our understanding of stem cell behavior has been the realization that regionalization of stem cells occurs early in development and this bias toward differentiation in phe- types of neurons or cells characteristic of a particular part of the brain appears to persist even after prolonged culture. We have therefore included additional chapters on olf- tory epithelial stem cells and retinal stem cells, both of which differ in their properties from ventricular zone and subventricular zone–derived neural stem cells. It is also now clear from an analysis of mutants and transgenics where the death or self-renewal pa- way is altered that cell death regulates stem cell number. As a consequence, this second edition includes a separate chapter on cell death that summarizes the important changes in the death pathway that occur as stem cells mature. The existing chapters in the book have also been extensively revised and updated by experts who have generously c- tributed their time and expertise. The chapters have been organized along the lines of our understanding of how the nervous system develops (Fig. 1, on p. vi).

Table of contents (15 chapters)

  • Defining Neural Stem Cells and Their Role in Normal Development of the Nervous System

    Temple, Sally

    Pages 1-28

  • Neural Stem Cells in the Adult Brain

    Lim, Daniel A. (et al.)

    Pages 29-47

  • Cellular and Molecular Properties of Multipotent Neural Stem Cells Throughout Ontogeny

    Pevny, Larysa Halyna

    Pages 49-65

  • Multipotent Stem Cells in the Embryonic Nervous System

    Jalali, Ali (et al.)

    Pages 67-95

  • Regulation of Neural Stem Cell Death

    Akhtar, Rizwan S. (et al.)

    Pages 97-122

Buy this book

eBook $99.00
price for USA (gross)
  • ISBN 978-1-59259-914-1
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $129.00
price for USA
  • ISBN 978-1-61737-593-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Neural Development and Stem Cells
Editors
  • Scott Lipnick
  • Mohan C. Vemuri
  • Melissa Carpenter
Series Title
Contemporary Neuroscience
Copyright
2006
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-59259-914-1
DOI
10.1385/1592599141
Softcover ISBN
978-1-61737-593-4
Edition Number
2
Number of Pages
468
Number of Illustrations and Tables
84 b/w illustrations
Topics