More than 1,900 Springer Protocols eBooks at just $9.99 each! Get yours today>>

Methods in Molecular Biology

Computational Biology of Transcription Factor Binding

Editors: Ladunga, Istvan (Ed.)

  • Guides scientists of all disciplines through the jungle of regulatory regions, ChIP-seq, about 200 motif discovery tools and others
  • Includes vital tricks-of-the-trade from experts well-versed in the technology whenever available
  • Provides cutting-edge protocols for computer biologists and for researchers who wish to communicate better with them
see more benefits

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-60761-854-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-60761-853-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-1-4939-6166-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Through great experimental difficulty, we’ve witnessed rapid, crucial developments at the intersection of computational biology, experimental technology, and statistics through which the vital process of transcriptional regulation can be further examined. In Computational Biology of Transcription Factor Binding, experts in the field examine the basic principles and provide detailed guidance for the computational analyses and biological interpretations of transcription factor binding, while disclosing critical practical information and caveats that are missing from many research publications. The volume serves not only computational biologists but experimentalists as well, who may want to better understand how to design and execute experiments and to communicate more effectively with computational biologists, computer scientists, and statisticians. Written for the highly successful Methods in Molecular Biology™ series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results in the lab. Authoritative and easy to use, Computational Biology of Transcription Factor Binding guides scientists working in this area and demands not only new experiments but also the re-annotation of existing experimental data and computational predictions leading to important ongoing, major paradigm changes for us all.

Reviews

From the reviews:

“Gives us an overview of transcription and its regulation. … The methods are very up-to-date and clearly presented by authors … . The use of tools for predicting transcription factors binding sites is also very carefully presented in a text that is accessible for beginners … . In summary, this book presents an important tool for entering the growing field of bioinformatics and its use for the study of transcription. … If we cannot read all books ever written, this one is a good choice.” (Carla Columbano Oliveira, Brazilian Journal of Pharmaceutical Sciences, Vol. 47 (2), Summer, 2011)

Table of contents (24 chapters)

  • An Overview of the Computational Analyses and Discovery of Transcription Factor Binding Sites

    Ladunga, Istvan

    Pages 1-22

  • Components and Mechanisms of Regulation of Gene Expression

    Yilmaz, Alper (et al.)

    Pages 23-32

  • Regulatory Regions in DNA: Promoters, Enhancers, Silencers, and Insulators

    Riethoven, Jean-Jack M.

    Pages 33-42

  • Three-Dimensional Structures of DNA-Bound Transcriptional Regulators

    Shrivastava, Tripti (et al.)

    Pages 43-55

  • Identification of Promoter Regions and Regulatory Sites

    Solovyev, Victor V. (et al.)

    Pages 57-83

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-60761-854-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-60761-853-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-1-4939-6166-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Computational Biology of Transcription Factor Binding
Editors
  • Istvan Ladunga
Series Title
Methods in Molecular Biology
Series Volume
674
Copyright
2010
Publisher
Humana Press
Copyright Holder
The Editor(s) (if applicable) and The Author(s) 2018
eBook ISBN
978-1-60761-854-6
DOI
10.1007/978-1-60761-854-6
Hardcover ISBN
978-1-60761-853-9
Softcover ISBN
978-1-4939-6166-5
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 454
Topics