Methods in Molecular Biology

Systems Biology in Drug Discovery and Development

Methods and Protocols

Editors: Yan, Qing (Ed.)

  • Focuses on direct application of systems biology approaches in drug development and clinical practice
  • Advances the goal of truly personalized medicine
  • Includes expert tips from successful labs from around the world
  • Part of the highly successful Methods in Molecular Biology™ series
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eBook $149.00
price for USA (gross)
  • ISBN 978-1-60761-800-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-60761-799-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Due to the failing “one-drug-fits-all” model, it has become increasingly necessary to develop personalized medicine that treats whole systems and brings the right drug to the right patient with the right dosages. In Systems Biology in Drug Discovery and Development: Methods and Protocols, leading experts provide a practical, state-of-the-art, and holistic view of the translation of systems biology into better drug discovery and personalized medical practice. While the first part of the book describes cutting-edge technologies and methods in the field, the second part illustrates how the technologies can be applied in science for disease understanding and therapeutic discovery. As a volume in the highly successful Methods in Molecular Biology™ series, this collection provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and up-to-date, Systems Biology in Drug Discovery and Development: Methods and Protocols covers topics from fundamental concepts to advanced technologies in order to best serve biomedical students and professionals at all levels who are interested in vital integrative studies in molecular biology, genetics, bioinformatics, bioengineering, biochemistry, physiology, pathology, microbiology, immunology, pharmacology, toxicology, drug discovery, and clinical medicine.

Reviews

From the reviews:

“This book describes state-of-the-art technologies and methods in molecular biology and the necessary integration of data … . The resultant book provides an effective resource for students, biologists, and physicians in multiple disciplines, as well as individuals involved in the drug development process. … This is a very effective and comprehensive guide to the advances in molecular biology methods and computational tools that model complex biological systems as a means to better understand disease mechanisms and identify appropriate drug candidates for individualized therapies.” (Rachel Renee Chennault, Doody’s Review Service, February, 2011)

Table of contents (17 chapters)

  • Proteomics and Systems Biology: Application in Drug Discovery and Development

    Chakravarti, Bulbul (et al.)

    Pages 3-28

  • Systems Biology Approaches and Tools for Analysis of Interactomes and Multi-target Drugs

    Schrattenholz, André (et al.)

    Pages 29-58

  • Systems Biology “On-the-Fly”: SILAC-Based Quantitative Proteomics and RNAi Approach in Drosophila melanogaster

    Cuomo, Alessandro (et al.)

    Pages 59-78

  • Systems Biology of Cell Behavior

    Valeyev, Najl V. (et al.)

    Pages 79-95

  • Computational Modeling in Systems Biology

    Vallabhajosyula, Ravishankar R. (et al.)

    Pages 97-120

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-60761-800-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-60761-799-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Systems Biology in Drug Discovery and Development
Book Subtitle
Methods and Protocols
Editors
  • Qing Yan
Series Title
Methods in Molecular Biology
Series Volume
662
Copyright
2010
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-60761-800-3
DOI
10.1007/978-1-60761-800-3
Hardcover ISBN
978-1-60761-799-0
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XII, 337
Topics