Oxidative Stress in Applied Basic Research and Clinical Practice

Studies on Cardiovascular Disorders

Editors: Sauer, Heinrich, Shah, Ajay M., Laurindo, Francisco R. M. (Eds.)

  • Cutting-edge research Contributions by leading scientists The present series of articles on oxidative stress in clinical practice summarizes the current knowledge in a rapidly evolving field.

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eBook $289.00
price for USA (gross)
  • ISBN 978-1-60761-600-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $369.00
price for USA
  • ISBN 978-1-60761-599-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $369.00
price for USA
  • ISBN 978-1-61779-707-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This collection of articles on oxidative stress in clinical practice surveys essential current research in what is a rapidly evolving field. As well as giving the reader a mechanistic overview of how oxidative stress affects cardiovascular disease, it analyzes the potential of a number of therapeutic options that target these pathways. Understanding the complexity of the cellular redox system could lead to the development of better targeted interventions that facilitate patient recovery. Even as large-scale clinical trials of so-called ‘simple’ antioxidant approaches such as vitamins C and E show that significant benefits for cardiovascular patients remain elusive, Studies on Cardiovascular Disorders demonstrates that such approaches are too simplistic. Beginning with a summary of redox signaling models that could induce the progression of redox-associated cardiovascular disorders, the volume moves on to examine redox-mediated protein modification under physiological and pathophysiological conditions. It provides an outline of the signaling pathways in cardiovascular development during embryogenesis, and what impact these might have in the differentiation process of resident cardiac and blastocyst derived stem cells. Further chapters detail our current knowledge of the influence the sensory nervous system exerts on the cardiovascular system, and the paradoxical role of mitochondria-derived ROS in cardiac protection. In all, almost 30 contributions cover issues as diverse as the antioxidant properties of statins in the heart and the oxidative risk factors for cardiovascular disease in women. A range of medical practitioners will find the contents of Studies on Cardiovascular Disorders provides illuminating insight into the Janus-faced role of ROS in the cardiovascular system.

Reviews

From the reviews:

“This is a collection of articles that provides insight into the evolving field of oxidative stress. … It is intended for students, physicians in training, clinicians, and cardiovascular researchers interested in oxidative stress. … This collection of articles with color diagrams provides a unique, well-organized, and clinically relevant resource on a vast range of topics relating to oxidative stress. This book will be a solid resource in this rapidly changing field.” (Paul Michael, Doody’s Review Service, February, 2011)

Table of contents (29 chapters)

  • The Evolving Concept of Oxidative Stress

    Castro Fernandes, Denise (et al.)

    Pages 1-41

  • Mechanisms of Redox Signaling in Cardiovascular Disease

    Charles, Rebecca L. (et al.)

    Pages 43-60

  • Reactive Oxygen and Nitrogen Species in Cardiovascular Differentiation of Stem Cells

    Sauer, Heinrich (et al.)

    Pages 61-85

  • Reactive Oxygen Species (ROS) and the Sensory Neurovascular Component

    Graepel, Rabea (et al.)

    Pages 87-107

  • Mitochondrial Reactive Oxygen Species in Myocardial Pre- and Postconditioning

    Cardoso, Ariel R. (et al.)

    Pages 109-123

Buy this book

eBook $289.00
price for USA (gross)
  • ISBN 978-1-60761-600-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $369.00
price for USA
  • ISBN 978-1-60761-599-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $369.00
price for USA
  • ISBN 978-1-61779-707-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Studies on Cardiovascular Disorders
Editors
  • Heinrich Sauer
  • Ajay M. Shah
  • Francisco R. M. Laurindo
Series Title
Oxidative Stress in Applied Basic Research and Clinical Practice
Copyright
2010
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-60761-600-9
DOI
10.1007/978-1-60761-600-9
Hardcover ISBN
978-1-60761-599-6
Softcover ISBN
978-1-61779-707-1
Series ISSN
2197-7224
Edition Number
1
Number of Pages
XVIII, 590
Topics