Methods in Molecular Biology

Antimicrobial Peptides

Methods and Protocols

Editors: Giuliani, Andrea, Rinaldi, Andrea C. (Eds.)

  • Includes contributions from scientists from different disciplines and backgrounds, from both industry and academia
  • Provides notes sections describing major sources of problems that may occur with a particular technique and how they can be identified and overcome
  • Describes techniques and methods that can be applied beyond the specific field of antimicrobial peptide research
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eBook $139.00
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  • ISBN 978-1-60761-594-1
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Hardcover $179.00
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  • ISBN 978-1-60761-593-4
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Softcover $179.00
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About this book

The action of antimicrobial peptides (AMPs), ranging from direct killing of invading pathogens to immune response modulation and other complex biological responses, has stimulated research and clinical interest for more than two decades, but the area is still burgeoning due to emerging discoveries in the functions, roles, and regulation of AMPs, thus making the study of antimicrobial peptides a multi-disciplinary and rapidly evolving field. In Antimicrobial Peptides: Methods and Protocols, leading investigators present a broad, up-to-date collection of current research and experimental methods for the isolation, characterization, production, and optimization of antimicrobial peptides. Additional chapters detail methodologies in several microscopy techniques, high-throughput screening, QSAR modeling, and computer-aided design used to study these compounds, while key review articles survey potential medical applications of antimicrobial peptides as innovative anti-infective and immunomodulatory agents, as well as emerging discoveries in their function, regulation, and roles in innate immunity. As a volume in the highly successful Methods in Molecular Biology™ series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.

Authoritative and wide-ranging in its applications, Antimicrobial Peptides: Methods and Protocols provides both an authoritative guide for lab work on AMPs or related substances and a useful collection of thought stimuli to inspire further scientific endeavours in a wide array of vital fields.

Table of contents (25 chapters)

  • Antimicrobial Peptides in Frog Skin Secretions

    Conlon, J. Michael (et al.)

    Pages 3-14

  • Purification of Antimicrobial Peptides from Human Skin

    Schröder, Jens-M.

    Pages 15-30

  • Strategies for the Isolation and Characterization of Antibacterial Lantibiotics

    Jabes, Daniela (et al.)

    Pages 31-45

  • Expression and Purification of Recombinant α-Defensins and α-Defensin Precursors in Escherichia coli

    Figueredo, Sharel (et al.)

    Pages 47-60

  • Production of Recombinant Antimicrobial Peptides in Bacteria

    Zorko, Mateja (et al.)

    Pages 61-76

Buy this book

eBook $139.00
price for USA (gross)
  • ISBN 978-1-60761-594-1
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.00
price for USA
  • ISBN 978-1-60761-593-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.00
price for USA
  • ISBN 978-1-4939-6128-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Antimicrobial Peptides
Book Subtitle
Methods and Protocols
Editors
  • Andrea Giuliani
  • Andrea C. Rinaldi
Series Title
Methods in Molecular Biology
Series Volume
618
Copyright
2010
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-60761-594-1
DOI
10.1007/978-1-60761-594-1
Hardcover ISBN
978-1-60761-593-4
Softcover ISBN
978-1-4939-6128-3
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XV, 424
Topics