Methods in Molecular Biology

Protein Networks and Pathway Analysis

Editors: Nikolsky, Yuri, Bryant, Julie (Eds.)

  • A broad overview of experimental and analytical methods of functional data analysis written by the leaders in the field
  • Details multiple aspects of biological networks, from collecting binary interactions to building algorithms and modeling
  • Provides a guide to real life and research applications of current methods of systems biology
  • Covers a wide range of cell-based assay formats and systems
  • Presents a modular approach to experimental design, covering model biological systems, screening modalities, detection technologies, and approaches to data analysis
  • Comprehensive guide to developing, running, and analyzing cell-based assays in high-throughput screening
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eBook $149.00
price for USA (gross)
  • ISBN 978-1-60761-175-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-60761-174-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-1-61779-488-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

From the beginning of the OMICs biology era, science has been pursuing the reduction of the complex "genome-wide" assays in order to understand the essential biology that lies beneath it.  In Protein Networks and Pathway Analysis, expert practitioners present a compilation of methods of functional data analysis, often referred to as "systems biology," and its applications in drug discovery, medicine and basic disease research.  The volume is divided into three convenient sections, covering the elucidation of protein, compound and gene interactions, analytical tools, including networks, interactome and ontologies, and applications of functional analysis.  As a volume in the highly successful Methods in Molecular Biology™ series, this work provides detailed descriptions and hands-on implementation advice.

 

Authoritative and cutting-edge, Protein Networks and Pathway Analysis presents both "wet lab" experimental methods and computational tools in order to cover a broad spectrum of issues in this fascinating new field.

Table of contents (20 chapters)

  • Mining Protein–Protein Interactions from Published Literature Using Linguamatics I2E

    Bandy, Judith (et al.)

    Pages 3-13

  • Relative Avidity, Specificity, and Sensitivity of Transcription Factor–DNA Binding in Genome-Scale Experiments

    Kuznetsov, Vladimir A.

    Pages 15-50

  • Curation of Inhibitor-Target Data: Process and Impact on Pathway Analysis

    Devidas, Sreenivas

    Pages 51-62

  • Profiling Protein Interaction Networks with Functional Protein Microarrays

    Mattoon, Dawn R. (et al.)

    Pages 63-74

  • Manual Annotation of Protein Interactions

    Bureeva, Svetlana (et al.)

    Pages 75-95

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-60761-175-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-60761-174-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-1-61779-488-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Protein Networks and Pathway Analysis
Editors
  • Yuri Nikolsky
  • Julie Bryant
Series Title
Methods in Molecular Biology
Series Volume
563
Copyright
2009
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-60761-175-2
DOI
10.1007/978-1-60761-175-2
Hardcover ISBN
978-1-60761-174-5
Softcover ISBN
978-1-61779-488-9
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XIV, 410
Number of Illustrations and Tables
118 b/w illustrations
Topics