Methods in Molecular Biology

Rat Genomics

Methods and Protocols

Editors: Anegon, Ignacio (Ed.)

  • Comprehensive and an easily accessible reference volume for developing, running, and analyzing biomedical research using the rat as model system

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eBook $129.00
price for USA (gross)
  • ISBN 978-1-60327-389-3
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.00
price for USA
  • ISBN 978-1-60327-388-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $169.00
price for USA
  • ISBN 978-1-61779-686-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Grown exponentially by the genomic revolution, the use of the rat as a model of choice for physiological studies continues in popularity and at a much greater depth of understanding. In Rat Genomics: Methods and Protocols, world-wide experts provide both practical information for researchers involved in genomic research in the rat along with a more contextual discussion about the usefulness of the rat in physiological or translational research in different organs and systems. The volume extensively covers topics including genome sequencing, quantitative trait loci mapping, and the identification of single nucleotide polymorphisms as well as the development of transgenic technologies such as nuclear cloning, lentiviral-mediated transgenesis, gene knock-down using RNA interference, gene knock-out by mutagenesis, and zinc finger nucleases plus exciting advances in the obtention of rat embryonic cell lines. As a volume in the highly successful Methods in Molecular Biology™ series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results.

Comprehensive and up-to-date, Rat Genomics: Methods and Protocols thoroughly covers the current techniques used in labs around the world and overviews the applications of the data obtained, making it certain to be useful to the scientific community as a key source of references and methods.

Table of contents (30 chapters)

  • The Rat: A Model Used in Biomedical Research

    Jacob, Howard J.

    Pages 1-11

  • Genetic Mapping and Positional Cloning

    Aitman, Timothy J. (et al.)

    Pages 13-32

  • Sequencing of the Rat Genome and Databases

    Worthey, Elizabeth A. (et al.)

    Pages 33-53

  • Design of Expression Cassettes for the Generation of Transgenic Animals (Including Insulators)

    Houdebine, Louis-Marie

    Pages 55-69

  • Inducible and Conditional Promoter Systems to Generate Transgenic Animals

    Hakamata, Yoji (et al.)

    Pages 71-79

Buy this book

eBook $129.00
price for USA (gross)
  • ISBN 978-1-60327-389-3
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.00
price for USA
  • ISBN 978-1-60327-388-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $169.00
price for USA
  • ISBN 978-1-61779-686-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Rat Genomics
Book Subtitle
Methods and Protocols
Editors
  • Ignacio Anegon
Series Title
Methods in Molecular Biology
Series Volume
597
Copyright
2010
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-60327-389-3
DOI
10.1007/978-1-60327-389-3
Hardcover ISBN
978-1-60327-388-6
Softcover ISBN
978-1-61779-686-9
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XVI, 462
Number of Illustrations and Tables
68 b/w illustrations, 2 illustrations in colour
Topics