The Receptors

The Dopamine Receptors

Editors: Neve, Kim (Ed.)

  • Relies heavily on new knowledge
  • The use of knock-out mice and subtype-selective drugs merit discussion in stand-alone chapters
  • The field of G protein-coupled receptors has advanced significantly since the publication of the first edition
  • Contains new chapters on dopamine receptor-interacting proteins and on dopamine receptor oligomerization
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eBook $269.00
price for USA (gross)
  • ISBN 978-1-60327-333-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $379.00
price for USA
  • ISBN 978-1-60327-332-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $379.00
price for USA
  • ISBN 978-1-61779-656-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Dopamine receptors are among the most validated drug targets for neuropsychiatric disorders such as schizophrenia and Parkinson’s disease, and are potential targets for other disorders such as substance abuse, depression, Tourette’s syndrome, and attention deficit hyperactivity disorder. The new knowledge brought from the creation and characterization of mice deficient in each of the subtypes and the development of increasingly subtype-selective agonists and antagonists has fueled many of the chapters new to this second edition, with the use of knock-out mice and subtype-selective drugs meriting discussion in stand-alone chapters. The field of G protein-coupled receptors has also advanced significantly since the first edition, with a model of GPCR signaling based on linear, compartmentalized pathways having been replaced by a more complex, richer model in which neurotransmitter effects are mediated by a signalplex composed of numerous signaling proteins, including multiple GPCRs, other types of receptors, such as ionotropic receptors, accessory and scaffolding proteins, and effectors. This second edition of Dopamine Receptors will be of interest to neurobiologists, pharmacologists and molecular biologists who study the brain, as well as neurologists working on psychiatric diseases.

Reviews

...extremely well-written and thoroughly referenced... All neuroscientists searching for an invaluable reference which provides a clearer understanding of the dopamine field and its future direction should have this book at their fingertips. -Journal of Medicinal Chemistry

Table of contents (19 chapters)

  • Historical Overview: Introduction to the Dopamine Receptors

    Seeman, Philip

    Pages 1-21

  • Gene and Promoter Structures of the Dopamine Receptors

    D’Souza, Ursula M.

    Pages 23-46

  • Structural Basis of Dopamine Receptor Activation

    Moreira, Irina S. (et al.)

    Pages 47-73

  • Dopamine Receptor Subtype-Selective Drugs: D1-Like Receptors

    Nichols, David E.

    Pages 75-99

  • Dopamine Receptor Subtype-Selective Drugs: D2-Like Receptors

    Prante, Olaf (et al.)

    Pages 101-135

Buy this book

eBook $269.00
price for USA (gross)
  • ISBN 978-1-60327-333-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $379.00
price for USA
  • ISBN 978-1-60327-332-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $379.00
price for USA
  • ISBN 978-1-61779-656-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
The Dopamine Receptors
Editors
  • Kim Neve
Series Title
The Receptors
Copyright
2010
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-60327-333-6
DOI
10.1007/978-1-60327-333-6
Hardcover ISBN
978-1-60327-332-9
Softcover ISBN
978-1-61779-656-2
Edition Number
2
Number of Pages
XII, 648
Number of Illustrations and Tables
63 b/w illustrations, 6 illustrations in colour
Topics