Neuromethods

Animal Models of Epilepsy

Methods and Innovations

Editors: Baraban, Scott C. (Ed.)

  • Provides an easily accessible reference for emerging animal models of epilepsy written by leading researchers in the field
  • Details the latest innovations and methodologies currently being applied in the field of epilepsy research
  • Covers a wide range of species and approaches
  • Presents a variety of experimental strategies, covering simple model organisms, imaging and modeling technologies, gene therapy and genetic approaches to animal model development
  • Moves beyond traditional animal models to encompass organisms and strategies that are at the cutting-edge of neuroscience
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eBook $139.00
price for USA (gross)
  • ISBN 978-1-60327-263-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.00
price for USA
  • ISBN 978-1-60327-262-9
  • Free shipping for individuals worldwide
  • Online orders shipping within 2-3 days.
About this book

With its complex anatomical, molecular, electrophysiological and behavioral components, epilepsy provides the neuroscientist with nearly boundless opportunities to examine basic neurobiological mechanisms. In Animal Models of Epilepsy: Methods and Innovations, prominent investigators in the field examine several novel models of epilepsy in mice as well as in genetically tractable "simple" species such as Drosophila melanogaster (fruit flies), Caenorhabditis elegans (worms), Xenopus laevis (tadpoles) and Danio rerio (zebrafish). While covering some traditional models, the volume also explores the newest innovations like modeling seizure activity in silica and advanced strategies for seizure detection and gene therapy. As a volume in the successful Neuromethods™ series, the chapters provide clear, step-by-step protocols and thought-provoking reviews of the most recent advancements in the field.

Comprehensive and cutting-edge, Animal Models of Epilepsy: Methods and Innovations is an ideal guide for scientists who wish to expand our understanding of the pathogenesis of this neurological disorder.

Reviews

From the reviews:

“As a clinical epileptologist interested in fundamental aspects of epilepsy, I obtained a thorough update on the several frontiers of current epilepsy research from this lucid volume. Basic scientists will profit from these 14 distinct and succinct reviews that also treat methodology and pitfalls in detail. Thus, this work is recommended for basic science and clinical epileptologists as well as students of these disciplines.” (Warren T. Blume, Canadian Journal of Neurological Sciences, Vol. 37 (4), July, 2010)

Table of contents (14 chapters)

  • The Nematode, Caenorhabditis elegans, as an Emerging Model for Investigating Epilepsy

    Locke, Cody J. (et al.)

    Pages 1-25

  • The Genetics and Molecular Biology of Seizure Susceptibility in Drosophila

    Song, Juan (et al.)

    Pages 27-43

  • The Albino Xenopus laevis Tadpole as a Novel Model of Developmental Seizures

    Hewapathirane, D. Sesath (et al.)

    Pages 45-57

  • Zebrafish as a Simple Vertebrate Organism for Epilepsy Research

    Baraban, Scott C.

    Pages 59-74

  • Modeling Tuberous Sclerosis Complex: Brain Development and Hyperexcitability

    Ess, Kevin C.

    Pages 75-86

Buy this book

eBook $139.00
price for USA (gross)
  • ISBN 978-1-60327-263-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.00
price for USA
  • ISBN 978-1-60327-262-9
  • Free shipping for individuals worldwide
  • Online orders shipping within 2-3 days.
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Bibliographic Information

Bibliographic Information
Book Title
Animal Models of Epilepsy
Book Subtitle
Methods and Innovations
Editors
  • Scott C. Baraban
Series Title
Neuromethods
Series Volume
40
Copyright
2009
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-60327-263-6
DOI
10.1007/978-1-60327-263-6
Hardcover ISBN
978-1-60327-262-9
Series ISSN
0893-2336
Edition Number
1
Number of Pages
XIII, 276
Number of Illustrations and Tables
39 b/w illustrations, 19 illustrations in colour
Topics