Methods in Molecular Biology

Bioinformatics Methods in Clinical Research

Editors: Matthiesen, Rune (Ed.)

  • Fully updated overview on machine learning techniques applied to biological problems
  • Includes detailed information about current standards for a number of clinical diseases
  • Presents details on data analysis strategies in genomics, transcriptomics, proteomics and metabolomics
  • Summarizes statistical methods and tools for enrichment/depletion analysis
  • Provides comprehensive coverage of biomedical text mining
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eBook $129.00
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  • ISBN 978-1-60327-194-3
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  • Immediate eBook download after purchase
Hardcover $169.00
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  • ISBN 978-1-60327-193-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $169.00
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  • ISBN 978-1-61779-670-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Integrated bioinformatics solutions have become increasingly valuable in past years, as technological advances have allowed researchers to consider the potential of omics for clinical diagnosis, prognosis, and therapeutic purposes, and as the costs of such techniques have begun to lessen.  In Bioinformatics Methods in Clinical Research, experts examine the latest developments impacting clinical omics, and describe in great detail the algorithms that are currently used in publicly available software tools. Chapters discuss statistics, algorithms, automated methods of data retrieval, and experimental consideration in genomics, transcriptomics, proteomics, and metabolomics. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, provides practical examples illustrating methods, results, and conclusions from data mining strategies wherever possible, and includes a Notes section which shares tips on troubleshooting and avoiding known pitfalls.

Informative and ground-breaking, Bioinformatics Methods in Clinical Research establishes a much-needed bridge between theory and practice, making it an indispensable resource for bioinformatics researchers.

Reviews

From the reviews:

“This volume of Methods in Molecular Biology provides an overview of the recent improvements in the use of bioinformatics in clinical research. … All chapters provide pertinent examples. … The book is intended primarily for scientists involved in biomedical informatics (computational biologists, biostatisticians, computer scientists) who are active in the field of clinical research. This includes both first-time and seasoned students and biomedical researchers who are interested in using bioinformatics. … It also presents a number of valuable approaches currently in use.” (Ruben Mestril, Doody’s Review Service, April, 2010)

“This book ‘Bioinformatics Methods in Clinical Research edited by Rune Matthiesen’ contains sixteen chapters, and results from scientific cooperation of academics, specialists in the main areas of investigation on bioinformatics methods, and applications in clinical research from centers and universities of Europe such as Denmark, Spain, Portugal as well as Canada and the United States of North America. … several specific fields are discussed including biomarkers in breast cancer and computational methods for two-dimensional analyses in gels.” (Sílvia Regina Cavani Jorge Santos, Brazilian Journal of Pharmaceutical Sciences, Spring, 2011)


Table of contents (16 chapters)

  • Introduction to Omics

    Gubb, Ewa (et al.)

    Pages 1-23

  • Machine Learning: An Indispensable Tool in Bioinformatics

    Inza, Iñaki (et al.)

    Pages 25-48

  • SNP-PHAGE: High-Throughput SNP Discovery Pipeline

    Aransay, Ana M. (et al.)

    Pages 49-65

  • R Classes and Methods for SNP Array Data

    Scharpf, Robert B. (et al.)

    Pages 67-79

  • Overview on Techniques in Cluster Analysis

    Frades, Itziar (et al.)

    Pages 81-107

Buy this book

eBook $129.00
price for USA (gross)
  • ISBN 978-1-60327-194-3
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.00
price for USA
  • ISBN 978-1-60327-193-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $169.00
price for USA
  • ISBN 978-1-61779-670-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Bioinformatics Methods in Clinical Research
Editors
  • Rune Matthiesen
Series Title
Methods in Molecular Biology
Series Volume
593
Copyright
2010
Publisher
Humana Press
Copyright Holder
Humana Press
Distribution Rights
Distribution rights for India: Mehul Book Sales, Mumbai, India
eBook ISBN
978-1-60327-194-3
DOI
10.1007/978-1-60327-194-3
Hardcover ISBN
978-1-60327-193-6
Softcover ISBN
978-1-61779-670-8
Series ISSN
1064-3745
Edition Number
1
Number of Pages
X, 390
Number of Illustrations and Tables
63 b/w illustrations
Topics