Methods in Molecular Biology

Pharmacogenomics in Drug Discovery and Development

Editors: Yan, Qing (Ed.)

  • Examines both fundamental concepts and advanced technologies in pharmacogenomics
  • Uses cutting-edge technologies to pursue systems-based pharmacogenomics, including bioinformatics, microarray, and association studies
  • Methodical, state-of-the-art contributions cover topics from individual molecules and gene-drug interactions to systemic diseases
  • Explores extensive applications of pharmacogenomics in drug development for diseases, including psychiatric disorders, cardiovascular diseases, cancer, Alzheimer's disease, rheumatoid arthritis, asthma, and infectious diseases
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eBook $149.00
price for USA (gross)
  • ISBN 978-1-59745-205-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.00
price for USA
  • ISBN 978-1-58829-887-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.00
price for USA
  • ISBN 978-1-61737-825-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Since each human is genetically distinctive, responding differently to disease-causing factors as well as drugs, the field pharmacogenomics arose to develop personalized medicine, or medicine that deals with the complexity of the human body.  In Pharmacogenomics in Drug Discovery and Development, leading experts present methodical, state-of-the-art contributions covering topics from individual molecules to systemic diseases, examining both fundamental concepts and advanced technologies.  Divided into three sections, the volume begins by exploring cutting-edge technologies used to pursue systems-based pharmacogenomics, followed by extensive chapters on gene-drug interactions and the use of pharmacogenomics in therapeutics of diseases. Although not in standard Methods in Molecular Biology™ series format, the book retains the practicality and usefulness of the highly successful series.

Comprehensive and up-to-date, Pharmacogenomics in Drug Discovery and Development is an ideal volume for scientists striving to transform disease treatment into disease prevention.

Reviews

From the reviews:

"This volume in the Methods in Molecular Biology series covers pharmacogenomics in drug discovery. … The book is intended for scientists in academic, industrial, and health care settings who are striving to transform disease treatment into disease prevention. … The advanced technologies are presented in a very detail manner, even including step-by-step protocols. … By covering topics from individual molecules to systemic diseases … this book provides an overview of current knowledge on the use of pharmacogenomics in therapeutics of disease." (Xiaobo Zhong, Doody’s Review Service, July, 2008)


Table of contents (17 chapters)

  • The Integration of Personalized and Systems Medicine

    Yan, Qing

    Pages 1-19

  • Applications of Microarrays and Biochips in Pharmacogenomics

    Hardiman, Gary

    Pages 21-30

  • Confounding in Genetic Association Studies and Its Solutions

    Hu, Donglei (et al.)

    Pages 31-39

  • Pharmacogenetics of Membrane Transporters

    Sissung, Tristan M. (et al.)

    Pages 41-62

  • Pharmacogenomics of Drug-Metabolizing Enzymes and Drug Transporters in Chemotherapy

    Bosch, Tessa M.

    Pages 63-76

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-59745-205-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.00
price for USA
  • ISBN 978-1-58829-887-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.00
price for USA
  • ISBN 978-1-61737-825-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Pharmacogenomics in Drug Discovery and Development
Editors
  • Qing Yan
Series Title
Methods in Molecular Biology
Series Volume
448
Copyright
2008
Publisher
Humana Press
Copyright Holder
Humana Press
Distribution Rights
Distribution rights for India: CBS Publishers, New Delhi, India
eBook ISBN
978-1-59745-205-2
DOI
10.1007/978-1-59745-205-2
Hardcover ISBN
978-1-58829-887-4
Softcover ISBN
978-1-61737-825-6
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XIII, 487
Topics