Methods in Molecular Biology

Structural Proteomics

High-Throughput Methods

Editors: Kobe, Bostjan, Guss, Mitchell, Huber, Thomas (Eds.)

  • First book of protocols to cover techniques in a new and emerging field
  • Offers step-by-step methods and protocols for reproducible lab experiments
  • Each protocol has a section where the major researchers in the field offer tricks and hints of the trade
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eBook $149.00
price for USA (gross)
  • ISBN 978-1-60327-058-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-58829-809-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-1-61737-789-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Structural genomics is a newly emerging field that has arisen following the successful footsteps of the major sequencing efforts generally bundled under the heading "genomics". In Structural Proteomics: High Throughput Methods, readers are provided with a current view of all aspects of the 'pipeline' that takes protein targets to structures and how these have been optimized. This volume includes chapters describing in-depth the individual steps in the Structural Genomics pipeline, as well as overviews of individual Structural Genomics initiatives. Topics include Target Selection for structural genomics, Protein structure modeling, High-throughput cloning, Mass Spectrometry modeling. Structural Proteomics: High Throughput Methods, encourages its readers to access further details on the methodologies in on-line resources as well as in cited literature making it an invaluable resource. Most methods in this important book are as amenable to small laboratories as to large consortia, and do not require major investments in facilities. This essential volume provides insight into the diversity of approaches adopted by different laboratories and proves that 'high throughput' is really the defining characteristic of structural genomics.

Reviews

From the reviews:

"This book compiles an impressive array of contributions from a variety of contributors … usually in a format that is accessible to any jobbing structural biologist, or those other molecular biologists with an linking to press their molecular targets into crystal screens or NMR tubes. … In sum, this is a book it is useful to have to hand … ." (Paul C. Driscoll, ChemBioChem, Issue 9, August, 2008)

"This book ... details some of the `tricks of the trade' involved in the field of structural genomics. ... This will be a useful text for laboratories already involved in fields covered in the book who want to increase the number of projects in the lab or for those who want to expand into neighbouring fields." (Darren Thompson, Microbiology Today, November, 2008)


Table of contents (39 chapters)

  • Target Selection for Structural Genomics: An Overview

    Marsden, Russell L. (et al.)

    Pages 3-25

  • A General Target Selection Method for Crystallographic Proteomics

    Robin, Gautier (et al.)

    Pages 27-35

  • Target Selection: Triage in the Structural Genomics Battlefield

    Raftery, James

    Pages 37-47

  • Data Management in Structural Genomics: An Overview

    Haquin, Sabrina (et al.)

    Pages 49-79

  • Data Deposition and Annotation at the Worldwide Protein Data Bank

    Dutta, Shuchismita (et al.)

    Pages 81-101

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-60327-058-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-58829-809-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-1-61737-789-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Structural Proteomics
Book Subtitle
High-Throughput Methods
Editors
  • Bostjan Kobe
  • Mitchell Guss
  • Thomas Huber
Series Title
Methods in Molecular Biology
Series Volume
426
Copyright
2008
Publisher
Humana Press
Copyright Holder
Humana Press
Distribution Rights
Distribution rights for India: CBS Publishers, New Delhi, India
eBook ISBN
978-1-60327-058-8
DOI
10.1007/978-1-60327-058-8
Hardcover ISBN
978-1-58829-809-6
Softcover ISBN
978-1-61737-789-1
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XXVI, 602
Number of Illustrations and Tables
120 b/w illustrations, 10 illustrations in colour
Topics