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Methods in Molecular Biology

Bioinformatics

Volume I: Data, Sequence Analysis and Evolution

Editors: Keith, Jonathan M. (Ed.)

  • Encompasses topics from across the diverse field of bioinformatics through its broad scope approach
  • Over 80 authors from around the globe contribute to the two volumes, including many leading experts in their respective subjects
  • An inter-disciplinary collaboration involving biologists, biochemists, physicists, mathematicians, statisticians and computer scientists
  • Contains simplified descriptions, requiring a minimum of background knowledge
  • References a wide variety of software tools and scripts, available online
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Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-60327-159-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-58829-707-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-1-61737-730-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Not only is the quantity of life science data expanding, but new types of biological data continue to be introduced as a result of technological development and a growing understanding of biological systems. Methods for analyzing these data are an increasingly important component of modern biological research. In Bioinformatics, leading researchers in the field provide a selection of the most useful and widely applicable methods, able to be applied as is, or with minor variations, to many specific problems.  Volume I: Data, Sequence Analysis and Evolution examines a selection of methods involving the generation and organization of data, including sequence data, RNA and protein structures, microarray expression data and functional annotations, methods for discovering the functional components of genomes, whether they be genes, alternative splice sites, non-coding RNAs or regulatory motifs, and several of the most interesting methods in phylogenetics and evolution.  As a volume of the highly successful Methods in Molecular Biology™ series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results.

Comprehensive and cutting-edge, Bioinformatics: Volume I: Data, Sequence Analysis and Evolution is an ideal reference for all scientists involved with the ever-growing array of data in the expanding field of life science.

Reviews

From the reviews:

"This precise description of all current molecular biology techniques is an important addition to the field of bioinformatics. The purpose is to provide a ‘detailed description and implantation advice’ about current molecular biology techniques. … the book is written primarily for students and beginning bioinformatics researchers. … The authors have included both an index and an evolution index at the end, which will be very helpful to readers. This is a very good reference for students who are beginning level bioinformatics researchers." (Basabi Rana, Doody’s Review Service, September, 2008)

"Bioinformatics is presented … with a total of 51 chapters. … successfully cover the wide field of bioinformatics, providing many useful methods, the majority of which are accessible to the non-specialist. … will serve as a valuable reference and therefore may be most appropriate as an institutional purchase." (Conrad Nieduszynski, Microbiology Today, February, 2009)

"Volume I comprises 24 chapters that describe topics in sequence analyses, phylogenetics, genome evolution, and gene expression analysis. … Several chapters highlight how to integrate and visualize local analyses … . give relatively in-depth coverage of many concepts that are applied by bioinformatics specialists. … Many of the chapters are example driven, with basic forays into bioinformatics analyses that will educate readers in both the theory and practical matter of running the analyses." (Jason E. Stajich, The Quarterly Review of Biology, Vol. 84, September, 2009)

“The goal of the book is to cover different types of data and their analysis methods for biological discovery, each of its 24 chapters is written by an expert in the field and can be read independently of the others. … describes the most widely used techniques. … easily accessible to a large audience involved in utilizing and developing bioinformatics. … a wonderful book for nonspecialists to enter the field of bioinformatics, but also a comprehensive handbook for specialists, when they need a good reference.” (Hsun-Hsien Chang, ACM Computing Reviews, June, 2009)

Table of contents (24 chapters)

  • Managing Sequence Data

    Mizrachi, Ilene Karsch

    Pages 3-27

  • RNA Structure Determination by NMR

    Scott, Lincoln G. (et al.)

    Pages 29-61

  • Protein Structure Determination by X-Ray Crystallography

    Ilari, Andrea (et al.)

    Pages 63-87

  • Pre-Processing of Microarray Data and Analysis of Differential Expression

    Durinck, Steffen

    Pages 89-110

  • Developing an Ontology

    Harris, Midori A.

    Pages 111-124

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-60327-159-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-58829-707-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-1-61737-730-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Bioinformatics
Book Subtitle
Volume I: Data, Sequence Analysis and Evolution
Editors
  • Jonathan M. Keith
Series Title
Methods in Molecular Biology
Series Volume
452
Copyright
2008
Publisher
Humana Press
Copyright Holder
Humana Press
Distribution Rights
Distribution rights In India: Ane Books India, New Delhi, India
eBook ISBN
978-1-60327-159-2
DOI
10.1007/978-1-60327-159-2
Hardcover ISBN
978-1-58829-707-5
Softcover ISBN
978-1-61737-730-3
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XII, 562
Number of Illustrations and Tables
133 b/w illustrations, 3 illustrations in colour
Topics