Methods in Molecular Biology

Telomerase Inhibition

Strategies and Protocols

Editors: Andrews, Lucy, Tollefsbol, Trygve (Eds.)

  • A compendium of the most recent and advanced methods applied to the rapidly expanding field of telomerase inhibition
  • Provides the researcher with a diverse and comprehensive set of tools
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eBook $109.00
price for USA (gross)
  • ISBN 978-1-60327-070-0
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  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.00
price for USA
  • ISBN 978-1-58829-683-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
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  • ISBN 978-1-61737-716-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Due in part to the selective nature of telomerase inhibition as an anticancer approach, the field has expanded considerably in the past decade. The recent advances in methods of telomerase inhibition encompass many different areas of research including molecular biology, cell biology, biochemistry, oncology and gerontology. Telomerase Inhibition provides methods and protocols for those researchers. The techniques described in this book should provide the researcher with a diverse and comprehensive set of tools with which to study telomerase inhibition. Leaders in the field provide recently developed methods that have widespread application such as targeting the telomerase holoenzyme, its RNA template and other elements associated with telomerase activity. Additional methods involving the screening of telomerase inhibitors and telomerase inhibition combined with other chemotherapeutic agents are presented. This text, on the cutting edge of the field, will provide investigators with the most recent methods applied to the expanding field of telomerase inhibition.

Reviews

From the reviews:

"This book contains 14 chapters by active players in the telomerase field. … Overall this book will be a useful resource for researchers performing telomerase-related experiments." (Lionel Guittat and Jean-Louis Mergny, ChemMedChem, Issue 3, 2008)


Table of contents (14 chapters)

  • Methods of Telomerase Inhibition

    Andrews, Lucy G. (et al.)

    Pages 1-8

  • Telomerase Inhibition by Synthetic Nucleic Acids and Chemosensitization in Human Bladder Cancer Cell Lines

    Kraemer, Kai (et al.)

    Pages 9-22

  • hTERT Knockdown in Human Embryonic Kidney Cells Using Double-Stranded RNA

    Lai, Serene R. (et al.)

    Pages 23-29

  • RNA Interference Using a Plasmid Construct Expressing Short-Hairpin RNA

    Lai, Serene R (et al.)

    Pages 31-37

  • Retrovirus-Mediated RNA Interference

    Cunningham, Amanda P. (et al.)

    Pages 39-46

Buy this book

eBook $109.00
price for USA (gross)
  • ISBN 978-1-60327-070-0
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.00
price for USA
  • ISBN 978-1-58829-683-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
price for USA
  • ISBN 978-1-61737-716-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Telomerase Inhibition
Book Subtitle
Strategies and Protocols
Editors
  • Lucy Andrews
  • Trygve Tollefsbol
Series Title
Methods in Molecular Biology
Series Volume
405
Copyright
2007
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-60327-070-0
DOI
10.1007/978-1-60327-070-0
Hardcover ISBN
978-1-58829-683-2
Softcover ISBN
978-1-61737-716-7
Series ISSN
1064-3745
Edition Number
1
Number of Pages
X, 193
Topics