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  • Book
  • © 2007

Topics in Biostatistics

  • Provides a framework for choosing appropriate biostatistical methods
  • Introduces advanced methods in statistics, including how to choose and work with statistical packages
  • Includes supplementary material: sn.pub/extras

Part of the book series: Methods in Molecular Biology (MIMB, volume 404)

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Table of contents (23 protocols)

  1. Front Matter

    Pages i-xii
  2. Study Design: The Basics

    • Hyun Ja Lim, Raymond G. Hoffmann
    Pages 1-17
  3. Observational Study Design

    • Raymond G. Hoffmann, Hyun Ja Lim
    Pages 19-31
  4. Descriptive Statistics

    • Todd G. Nick
    Pages 33-52
  5. Statistical Inference on Categorical Variables

    • Susan M. Perkins
    Pages 73-88
  6. Development and Evaluation of Classifiers

    • Todd A. Alonzo, Margaret Sullivan Pepe
    Pages 89-116
  7. Comparison of Means

    • Nancy Berman
    Pages 117-142
  8. Correlation and Simple Linear Regression

    • Lynn E. Eberly
    Pages 143-164
  9. Multiple Linear Regression

    • Lynn E. Eberly
    Pages 165-187
  10. General Linear Models

    • Edward H. Ip
    Pages 189-211
  11. Linear Mixed Effects Models

    • Ann L. Oberg, Douglas W. Mahoney
    Pages 213-234
  12. Design and Analysis of Experiments

    • Jonathan J. Shuster
    Pages 235-259
  13. Analysis of Change

    • James J. Grady
    Pages 261-271
  14. Logistic Regression

    • Todd G. Nick, Kathleen M. Campbell
    Pages 273-301
  15. Survival Analysis

    • Hongyu Jiang, Jason P. Fine
    Pages 303-318
  16. Basic Bayesian Methods

    • Mark E. Glickman, David A. van Dyk
    Pages 319-338
  17. Overview of Missing Data Techniques

    • Ralph B. D’Agostino Jr.
    Pages 339-352
  18. Statistical Topics in the Laboratory Sciences

    • Curtis A. Parvin
    Pages 353-375
  19. Power and Sample Size

    • L. Douglas Case, Walter T. Ambrosius
    Pages 377-408

About this book

Basic Biostatistics presents a multidisciplinary survey of biostatics methods, each illustrated with hands-on examples. Methods range from the elementary, including descriptive statistics, study design, statistical interference, categorical variables, evaluation of diagnostic tests, comparison of means, linear regression, and logistic regression. These introductory methods create a portfolio of biostatistical techniques for both novice and expert researchers. More complicated statistical methods are introduced as well, including those requiring either collaboration with a biostatistician or the use of a statistical package. Specific topics of interest include microarray analysis, missing data techniques, power and sample size, statistical methods in genetics. Expert advice is given on when to seek statistical help, and how to conduct a meeting with the statistical collaborator or consultant. Basic Biostatistics is an essential resource for researchers at every level of their career.

Reviews

From the reviews:

"It is useful to biologists as well as statisticians. The book describes the use of appropriate statistical methods and offers guidelines on selecting an appropriate test. … The main strength of the book is the clear exposition of statistical tests. … As biostatisticians we strongly recommend this book for libraries where research on molecular biology is going on, and students … in biostatistics. … helpful in understanding the essence of the statistical techniques to a wide range of researchers and students in biology and medicine." (Mukesh Srivastava and M. Abbas, Journal of Applied Statistics, Vol. 36 (4), April, 2009)

Editors and Affiliations

  • Department of Biostatistical Sciences, Wake Forest University Health Sciences, Winston-Salem

    Walter T. Ambrosius

Bibliographic Information

  • Book Title: Topics in Biostatistics

  • Editors: Walter T. Ambrosius

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-59745-530-5

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Humana Press 2007

  • Hardcover ISBN: 978-1-58829-531-6Published: 06 July 2007

  • Softcover ISBN: 978-1-61737-623-8Published: 19 November 2010

  • eBook ISBN: 978-1-59745-530-5Published: 03 February 2008

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XII, 528

  • Topics: Cell Biology

Buy it now

Buying options

eBook USD 189.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 249.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access