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Methods in Molecular Biology

Chiral Separations

Methods and Protocols

Editors: Gübitz, Gerald, Schmid, Martin G. (Eds.)

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  • ISBN 978-1-59259-648-5
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Hardcover $179.00
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Softcover $179.00
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  • ISBN 978-1-61737-390-9
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About this book

Methods for enantiomer separation are very important for controlling synthesis, for checking racemization, for enantiomeric purity control, and for pharmacokinetic studies. In Chiral Separations: Methods and Protocols, prominent experts from around the world detail the chromatographic and electroseparation techniques they have developed for chiral separations on an analytical scale. Described in step-by-step detail to ensure successful experimental results, the procedures are presented as either general methods or as specific applications to substance classes and special compounds, with emphasis on high performance liquid chromatography and capillary electrophoresis techniques, but also including thin layer chromotogrphic, gas chromatographic, and supercritical fluid chromatographic as well as recent electrochromotographic techniques. Each fully tested protocol includes an introduction to the principle underlying the method, equipment and reagent lists, and helpful notes on troubleshooting and avoiding known pitfalls.
Up-to-date and highly practical, Chiral Separations: Methods and Protocols will help both novice and advanced users not only choose optimal methods for their separation problems, but also readily obtain successful results.

Reviews

"It is an excellent book, and can be recommended for every laboratory involved in the synthesis and analysis of chiral compounds. Moreover, the editors have succeeded in getting internationally known leading experts to write the contributions." -Angewandte Chemie

"...will undoubtedly be of value to those who need to find useful ways to carry out such separations." -Journal of Medicinal Chemistry

"...this book is a useful compendium of chiral methods and will be of use to many workers in the field." - Biomed Chronatogr

Table of contents (25 chapters)

  • Chiral Separation Principles

    Gübitz, Gerald (et al.)

    Pages 1-28

  • Separation of Enantiomers by Thin-Layer Chromatography

    Günther, Kurt (et al.)

    Pages 29-59

  • Cyclodextrin-Based Chiral Stationary Phases for Liquid Chromatography

    Mitchell, Clifford R. (et al.)

    Pages 61-112

  • Enantiomeric Separations by HPLC Using Macrocyclic Glycopeptide-Based Chiral Stationary Phases

    Xiao, Tom Ling (et al.)

    Pages 113-171

  • Chiral Separation by HPLC Using Polysaccharide-Based Chiral Stationary Phases

    Yamamoto, Chiyo (et al.)

    Pages 173-181

Buy this book

eBook $139.00
price for USA (gross)
  • ISBN 978-1-59259-648-5
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.00
price for USA
  • ISBN 978-1-58829-150-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.00
price for USA
  • ISBN 978-1-61737-390-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Chiral Separations
Book Subtitle
Methods and Protocols
Editors
  • Gerald Gübitz
  • Martin G. Schmid
Series Title
Methods in Molecular Biology
Series Volume
243
Copyright
2004
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-59259-648-5
DOI
10.1385/1592596487
Hardcover ISBN
978-1-58829-150-9
Softcover ISBN
978-1-61737-390-9
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XIV, 432
Topics