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Biologic Therapy of Leukemia

  • Book
  • © 2003

Overview

Editors:
  1. Matt Kalaycio

    1. Leukemia Program, Department of Hematology and Medical Oncology, Cleveland Clinic Foundation, Cleveland, USA

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Part of the book series: Contemporary Hematology (CH)

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-xii
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  2. Immunotherapy

    1. Front Matter

      Pages 1-1
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    2. Human Leukemia-Derived Dendritic Cells as Tools for Therapy

      • David Claxton
      Pages 3-12

    3. The Graft vs Leukemia Effect

      • Brian J. Bolwell
      Pages 13-27

    4. Unconjugated Monoclonal Antibodies

      • Matt Kalaycio
      Pages 29-42

    5. Drug Immunoconjugate Therapy of Acute Myeloid Leukemia

      • Arthur E. Frankel, Bayard L. Powell, Eli Estey, Martin S. Tallman
      Pages 43-58

    6. Radiolabeled Monoclonal Antibodies

      • John M. Burke, Joseph G. Jurcic
      Pages 59-77

  3. Cytokines

    1. Front Matter

      Pages 79-79
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    2. Interferons

      • Thomas Fischer
      Pages 81-91

    3. Interleukin-2 Treatment of Acute Leukemia

      • Peter Kabos, Gary J. Schiller
      Pages 93-105

  4. Targeted Therapeutics

    1. Front Matter

      Pages 107-107
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    2. Antisense Therapy

      • Stanley R. Frankel
      Pages 109-126

    3. Signal Transduction Inhibitors

      • Michael E. O’Dwyer, Brian J. Druker
      Pages 127-144

    4. P-Glycoprotein Inhibition in Acute Myeloid Leukemia

      • Thomas R. Chauncey
      Pages 145-162

    5. Targeting the Apoptotic Machinery as a Potential Antileukemic Strategy

      • Benjamin M. F. Mow, Scott H. Kaufmann
      Pages 163-186

  5. Differentiation Agents

    1. Front Matter

      Pages 187-187
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    2. Arsenicals

      • Chadi Nabhan, Martin S. Tallman
      Pages 189-203

    3. All-Trans-Retinoic Acid in the Treatment of Acute Promyelocytic Leukemia

      • Pierre Fenaux, Laurent Degos
      Pages 205-222

  6. Gene Therapy

    1. Front Matter

      Pages 223-223
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    2. Gene Therapy

      • Paul J. Orchard, R. Scott Mclvor
      Pages 225-259
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Keywords

About this book

Exciting new "biologic" therapies for treating leukemia are appearing so rapidly that clinicians often find it difficult to make informed decisions about their use when making patient treatment decisions. Biologic Therapy of Leukemia summarizes and reviews all the available data concerning these cutting-edge biologic therapies so that practicing clinicians can make the correct patient-care choices. Here the busy physician will find in one convenient place crucial information on the uses and limitations of the major biologic therapies for leukemia, the different biologic strategies for its treatment, the management of patients being treated with such biologic agents, and the current and future role of emerging biologic agents.

Reviews

"...provides an in depth review of the biologic approaches that are entering the treatment arena for leukemia. The authors have done an excellent job of reviewing the current state of this therapeutic approach." - Medical Oncology

Editors and Affiliations

  • Leukemia Program, Department of Hematology and Medical Oncology, Cleveland Clinic Foundation, Cleveland, USA

    Matt Kalaycio

Bibliographic Information

  • Book Title: Biologic Therapy of Leukemia

  • Editors: Matt Kalaycio

  • Series Title: Contemporary Hematology

  • DOI: https://doi.org/10.1007/978-1-59259-383-5

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 2003

  • Hardcover ISBN: 978-1-58829-071-7Published: 04 April 2003

  • Softcover ISBN: 978-1-4684-9777-9Published: 24 July 2012

  • eBook ISBN: 978-1-59259-383-5Published: 04 April 2003

  • Edition Number: 1

  • Number of Pages: XII, 270

  • Number of Illustrations: 24 b/w illustrations

  • Topics: Hematology

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