Overview
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1845)
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Table of contents (16 protocols)
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Front Matter
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Back Matter
Keywords
About this book
This volume explores the various methods used to study tertiary lymphoid structures (TLS) in pathological situations. Pre-clinical models are also discussed in detail to show how TLS structure, development, and maintenance can be targeted and studied in vivo. The chapters in this book cover topics such as humans and mice; strategies to quantify TLS in order to use it in stained tissue sections; classifying a gene signature form fixed and paraffin-embedded tissues; and development of murine inflammatory models to help look at TLS in the context of infection or malignancy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and thorough, Tertiary Lymphoid Structures: Methods and Protocols is a valuable resource that increases the reader’s knowledge on immune functions and how they will pave the way to future therapeutic applications.
Editors and Affiliations
Bibliographic Information
Book Title: Tertiary Lymphoid Structures
Book Subtitle: Methods and Protocols
Editors: Marie-Caroline Dieu-Nosjean
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-8709-2
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2018
Hardcover ISBN: 978-1-4939-8708-5Published: 24 August 2018
Softcover ISBN: 978-1-4939-9372-7Published: 10 December 2019
eBook ISBN: 978-1-4939-8709-2Published: 23 August 2018
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XII, 289
Number of Illustrations: 4 b/w illustrations, 34 illustrations in colour
Topics: Immunology