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Preclinical MRI

Methods and Protocols

  • Book
  • © 2018

Overview

Editors:
  1. María Luisa García Martín

    1. BIONAND, Andalusian Centre for Nanomedicine and Biotechnology, Junta de Andalucía, Universidad de Málaga, Spain

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    You can also search for this editor in PubMed   Google Scholar

  2. Pilar López Larrubia

    1. Instituto de Investigaciones Biomédicas “Alberto Sols”, CSIC/UAM, Spain

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Includes cutting-edge methods and protocols
  • provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Methods in Molecular Biology (MIMB, volume 1718)

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Table of contents (27 protocols)

  1. Front Matter

    Pages i-xiv
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  2. MRI Basics

    1. Front Matter

      Pages 1-1
      Download chapter PDF

    2. Introduction to MRI Physics

      • Gary V. Martinez
      Pages 3-19

    3. Basic Pulse Sequences in Magnetic Resonance Imaging

      • Daniel Calle, Teresa Navarro
      Pages 21-37

  3. Perfusion, Diffusion and Functional MRI

    1. Front Matter

      Pages 39-39
      Download chapter PDF

    2. Dynamic Susceptibility Contrast MRI in Small Animals

      • Pilar López-Larrubia
      Pages 41-57

    3. Preclinical Arterial Spin Labeling Measurement of Cerebral Blood Flow

      • Eric R. Muir
      Pages 59-70

    4. Dynamic Contrast-Enhanced MRI

      • Jennifer Moroz, Stefan A. Reinsberg
      Pages 71-87

    5. Diffusion-Weighted Magnetic Resonance Imaging

      • Irene Guadilla, Daniel Calle, Pilar López-Larrubia
      Pages 89-101

    6. Diffusion Tensor Imaging (DTI)

      • Silvia Lope-Piedrafita
      Pages 103-116

    7. Mapping Functional Connectivity in the Rodent Brain Using Electric-Stimulation fMRI

      • Laura Pérez-Cervera, José María Caramés, Luis Miguel Fernández-Mollá, Andrea Moreno, Begoña Fernández, Elena Pérez-Montoyo et al.
      Pages 117-134

    8. Functional Diffusion Magnetic Resonance Imaging

      • Rita Maria Rocha Oliveira, Irene Guadilla, Pilar López-Larrubia
      Pages 135-147

  4. In Vivo Spectroscopy

    1. Front Matter

      Pages 149-149
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    2. In Vivo 1H Magnetic Resonance Spectroscopy

      • M. Carmen Muñoz-Hernández, María Luisa García-Martín
      Pages 151-167

    3. In Vivo Heteronuclear Magnetic Resonance Spectroscopy

      • Blanca Lizarbe, Antoine Cherix, Rolf Gruetter
      Pages 169-187

    4. 1H Spectroscopic Imaging of the Rodent Brain

      • Rui V. Simões, Emma Muñoz-Moreno, Raúl Tudela, Guadalupe Soria
      Pages 189-202

  5. Special MRI Techniques

    1. Front Matter

      Pages 203-203
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    2. Susceptibility Weighted MRI in Rodents at 9.4 T

      • Ferdinand Schweser, Marilena Preda, Robert Zivadinov
      Pages 205-234

    3. Biomedical 19F MRI Using Perfluorocarbons

      • Tuba Güden-Silber, Sebastian Temme, Christoph Jacoby, Ulrich Flögel
      Pages 235-257

    4. Rodent Abdominal Adipose Tissue Imaging by MR

      • Bhanu Prakash KN, Jadegoud Yaligar, Sanjay K. Verma, Venkatesh Gopalan, S. Sendhil Velan
      Pages 259-268
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Keywords

About this book

This volume discusses a variety of preclinical MRI methods and protocols to help technicians and researchers conduct studies in their respective fields. This book is organized into 7 parts: Part 1 covers the basics of MRI physics, relaxation, image contrast, and main acquisition sequences; Part 2 describes methodologies for diffusion, perfusion, and functional imaging; Part 3 looks at in vivo spectroscopy; Part 4 explores special MRI techniques that are less known in the field; Parts 5 and 6 discuss MRIs and MRSs in animal models of disease and the applications used to study them, and Part 7 looks at anesthesia and advanced contrast agents. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Comprehensive and thorough, Preclinical MRI: Methods and Protocols is a valuable resource for researchers interested in expanding their knowledge in this developing field.



Editors and Affiliations

  • BIONAND, Andalusian Centre for Nanomedicine and Biotechnology, Junta de Andalucía, Universidad de Málaga, Spain

    María Luisa García Martín

  • Instituto de Investigaciones Biomédicas “Alberto Sols”, CSIC/UAM, Spain

    Pilar López Larrubia

Bibliographic Information

  • Book Title: Preclinical MRI

  • Book Subtitle: Methods and Protocols

  • Editors: María Luisa García Martín, Pilar López Larrubia

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-4939-7531-0

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC 2018

  • Hardcover ISBN: 978-1-4939-7530-3Published: 16 January 2018

  • Softcover ISBN: 978-1-4939-8512-8Published: 06 June 2019

  • eBook ISBN: 978-1-4939-7531-0Published: 16 January 2018

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XIV, 464

  • Number of Illustrations: 39 b/w illustrations, 84 illustrations in colour

  • Topics: Imaging / Radiology

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