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  • © 2017

Metals in the Brain

Measurement and Imaging

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Neuromethods (NM, volume 124)

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Table of contents (14 protocols)

  1. Front Matter

    Pages i-xii
  2. Introduction and Overview

    • Anthony R. White
    Pages 1-6
  3. X-Ray Microscopy for Detection of Metals in the Brain

    • Joanna F. Collingwood, Freddy Adams
    Pages 7-32
  4. Fluorescent Probes for the Analysis of Labile Metals in Brain Cells

    • Jacek L. Kolanowski, Clara Shen, Elizabeth J. New
    Pages 51-70
  5. Probing Biological Trace Metals with Fluorescent Indicators

    • Christoph J. Fahrni, Daisy Bourassa, Ryan Dikdan
    Pages 71-107
  6. Lead Uptake and Localization in Glial Cell Cultures

    • Rola Barhoumi, Robert Taylor, Evelyn Tiffany-Castiglioni
    Pages 151-160
  7. Evaluating Iron Flux in the Brain

    • Bruce X. Wong, Linh Q. Lam, Andrew Tsatsanis, James A. Duce
    Pages 161-193
  8. Current Methods Used to Probe and Quantify Intracellular Total and Free Zn(II) Dynamics, and Subcellular Distribution in Cultured Neurons

    • Yan Qin, Kyle R. Gee, Qiaoling Jin, Barry Lai, Cheng Qian, Robert A. Colvin
    Pages 195-224
  9. Treatment and Measurement of Metals in Brain Cell Cultures

    • Xin Yi Choo, Alexandra Grubman
    Pages 259-268
  10. Back Matter

    Pages 269-270

About this book

This volume explores methods used to examine metal levels and distribution in brain tissue or brain-derived cells. The chapters in this book discuss the use of fluorescent metal probes, synchrotron-based X-ray microscopy, ICP-MS, laser ablation-ICP-MS, laser-based tissue microdissection, MRI image analysis, fractionation of cell tissue samples for metal analysis, and metal treatment of cells. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory.

Practical and cutting-edge, Metals in the Brain: Measurement and Imaging is a valuable resource for researchers in the rapidly growing area of neuroscience research.

Editors and Affiliations

  • Department of Pathology, University of Melbourne, Melbourne, Australia

    Anthony R. White

Bibliographic Information

  • Book Title: Metals in the Brain

  • Book Subtitle: Measurement and Imaging

  • Editors: Anthony R. White

  • Series Title: Neuromethods

  • DOI: https://doi.org/10.1007/978-1-4939-6918-0

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media LLC 2017

  • Hardcover ISBN: 978-1-4939-6916-6Published: 05 April 2017

  • Softcover ISBN: 978-1-4939-8338-4Published: 20 July 2018

  • eBook ISBN: 978-1-4939-6918-0Published: 04 April 2017

  • Series ISSN: 0893-2336

  • Series E-ISSN: 1940-6045

  • Edition Number: 1

  • Number of Pages: XII, 270

  • Number of Illustrations: 27 b/w illustrations, 31 illustrations in colour

  • Topics: Neurosciences

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 159.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access