Editors:
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
- Includes supplementary material: sn.pub/extras
Part of the book series: Methods in Molecular Biology (MIMB, volume 1558)
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Table of contents (22 protocols)
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Front Matter
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Fundamentals of Protein Bioinformatics
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Front Matter
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Protein PTM (Post-Translational Modification) Bioinformatics
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Front Matter
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Protein Network Bioinformatics
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Front Matter
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About this book
This volume introduces bioinformatics research methods for proteins, with special focus on protein post-translational modifications (PTMs) and networks. This book is organized into four parts and covers the basic framework and major resources for analysis of protein sequence, structure, and function; approaches and resources for analysis of protein PTMs, protein-protein interactions (PPIs) and protein networks, including tools for PPI prediction and approaches for the construction of PPI and PTM networks; and bioinformatics approaches in proteomics, including computational methods for mass spectrometry-based proteomics and integrative analysis for alternative splice isoforms, for functional discovery. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory or computational protocols, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and thorough, Protein Bioinformatics: From Protein Modifications and Networks to Proteomics is a valuable resource for readers who wish to learn about state-of-the-art bioinformatics databases and tools, novel computational methods, and future trends in protein and proteomic data analysis in systems biology. This book is useful to researchers who work in the biotechnology and pharmaceutical industries, and in various academic departments, such as biological and medical sciences and computer sciences and engineering.
Editors and Affiliations
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Center for Bioinformatics and Computational Biology, University of Delaware, Newark, USA
Cathy H. Wu, Cecilia N. Arighi
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Department of Biochemistry and Molecular and Cellular Biology, Georgetown University Medical Center, Washington, USA
Karen E. Ross
Bibliographic Information
Book Title: Protein Bioinformatics
Book Subtitle: From Protein Modifications and Networks to Proteomics
Editors: Cathy H. Wu, Cecilia N. Arighi, Karen E. Ross
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-6783-4
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media LLC 2017
Hardcover ISBN: 978-1-4939-6781-0Published: 03 February 2017
Softcover ISBN: 978-1-4939-8299-8Published: 19 July 2018
eBook ISBN: 978-1-4939-6783-4Published: 20 January 2017
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XIV, 472
Number of Illustrations: 3 b/w illustrations, 127 illustrations in colour
Topics: Bioinformatics