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  • Book
  • © 2017

Cancer Gene Networks

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
  • Includes supplementary material: sn.pub/extras

Part of the book series: Methods in Molecular Biology (MIMB, volume 1513)

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Table of contents (17 protocols)

  1. Front Matter

    Pages i-xii
  2. Introduction: Cancer Gene Networks

    • Robert Clarke
    Pages 1-9
  3. Emerging Methods in Chemoproteomics with Relevance to Drug Discovery

    • Chuong Nguyen, Graham M. West, Kieran F. Geoghegan
    Pages 11-22
  4. ANXA7-GTPase as Tumor Suppressor: Mechanisms and Therapeutic Opportunities

    • Ximena Leighton, Ofer Eidelman, Catherine Jozwik, Harvey B. Pollard, Meera Srivastava
    Pages 23-35
  5. Targeting Deubiquitinating Enzymes and Autophagy in Cancer

    • Ashley Mooneyham, Martina Bazzaro
    Pages 49-59
  6. Transcriptome and Proteome Analyses of TNFAIP8 Knockdown Cancer Cells Reveal New Insights into Molecular Determinants of Cell Survival and Tumor Progression

    • Timothy F. Day, Rajshree R. Mewani, Joshua Starr, Xin Li, Debyani Chakravarty, Habtom Ressom et al.
    Pages 83-100
  7. Network-Oriented Approaches to Anticancer Drug Response

    • Paola Lecca, Angela Re
    Pages 101-117
  8. CRISPR/Cas-Mediated Knockin in Human Pluripotent Stem Cells

    • Nipun Verma, Zengrong Zhu, Danwei Huangfu
    Pages 119-140
  9. Complete Transcriptome RNA-Seq

    • David F. B. Miller, Pearlly Yan, Fang Fang, Aaron Buechlein, Karl Kroll, David Frankhouser et al.
    Pages 141-162
  10. Computational Methods and Correlation of Exon-skipping Events with Splicing, Transcription, and Epigenetic Factors

    • Jianbo Wang, Zhenqing Ye, Tim H. Huang, Huidong Shi, Victor X. Jin
    Pages 163-170
  11. Tissue Engineering Platforms to Replicate the Tumor Microenvironment of Multiple Myeloma

    • Wenting Zhang, Woo Y. Lee, Jenny Zilberberg
    Pages 171-191
  12. microRNA Target Prediction

    • William Ritchie
    Pages 193-200
  13. Evaluating the Delivery of Proteins to the Cytosol of Mammalian Cells

    • Andrea L. J. Marschall, Congcong Zhang, Stefan Dübel
    Pages 201-208
  14. Validation of Biomarker Proteins Using Reverse Capture Protein Microarrays

    • Catherine Jozwik, Ofer Eidelman, Joshua Starr, Harvey B. Pollard, Meera Srivastava
    Pages 209-222
  15. Chemical Synthesis of Activity-Based Diubiquitin Probes

    • Guorui Li, Libo Yuan, Zhihao Zhuang
    Pages 223-232
  16. Back Matter

    Pages 243-248

About this book

This volume is a valuable and timely resource for a broad audience with interests in basic and translational cancer biology, cancer drug development, as well as in the practice of personalized oncology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

 

Authoritative and cutting-edge, Cancer Gene Networks aims to ensure successful results in the further study of this evolving and vital field. Ultimately these efforts will guide development of transformative strategies for cancer diagnosis and treatment.

Editors and Affiliations

  • Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, USA

    Usha Kasid, Robert Clarke

Bibliographic Information

  • Book Title: Cancer Gene Networks

  • Editors: Usha Kasid, Robert Clarke

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-4939-6539-7

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media New York 2017

  • Hardcover ISBN: 978-1-4939-6537-3Published: 03 November 2016

  • Softcover ISBN: 978-1-4939-8230-1Published: 27 June 2018

  • eBook ISBN: 978-1-4939-6539-7Published: 02 November 2016

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XII, 248

  • Number of Illustrations: 19 b/w illustrations, 41 illustrations in colour

  • Topics: Cancer Research

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access