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  • © 2011

Adult Acute Lymphocytic Leukemia

Biology and Treatment

  • Focused on acute lymphocytic leukemia in adults
  • Explores current controversies in treatment
  • Discusses the indications for allogeneic bone marrow transplantation
  • Examines the factors influencing treatment decisions
  • Provides expert insight on discoveries in new molecular strategies and treatment

Part of the book series: Contemporary Hematology (CH)

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Table of contents (24 chapters)

  1. Front Matter

    Pages i-xvi
  2. Acute Lymphocytic Leukemia – Clinical Features and Making the Diagnosis

    • Olga Frankfurt, LoAnn Petersen, Martin S. Tallman
    Pages 9-24
  3. The Biology of Adult Acute Lymphoblastic Leukemia

    • Jerald P. Radich, Olga Sala
    Pages 25-44
  4. Minimal Residual Disease in Acute Lymphoblastic Leukemia

    • Patrick A. Zweidler-McKay, Michael J. Borowitz
    Pages 45-60
  5. Cytogenetics

    • Anthony V. Moorman, Christine J. Harrison
    Pages 61-75
  6. Acute Lymphoblastic Leukemia: Epidemiology

    • Matthew J. Hourigan, Anthony H. Goldstone
    Pages 77-87
  7. The Generalized Care of the Patient with Acute Lymphoblastic Leukemia

    • Anthony R. Mato, Alicia K. Morgans, Selina M. Luger
    Pages 97-114
  8. Treatment of Acute Lymphoblastic Leukemia in Middle-Age and Older Adults

    • Vaishalee P. Kenkre, Richard A. Larson
    Pages 115-126
  9. Pharmacology of Acute Lymphoblastic Leukemia Therapy

    • Paul M. Barr, Richard J. Creger, Nathan A. Berger
    Pages 127-144
  10. Assessment of Response to Treatment

    • Christopher P. Fox, A. K. McMillan
    Pages 145-156
  11. T-Cell Acute Lymphoblastic Leukemia

    • Andrei R. Shustov, Frederick R. Appelbaum
    Pages 157-174
  12. Burkitt Lymphoma and Leukemia

    • Kevin A. David, Mark Roberts, LoAnn C. Peterson, Andrew M. Evens
    Pages 175-210
  13. Treatment of Acute Lymphoblastic Leukemia in Young Adults

    • Nicolas Boissel, Françoise Huguet, Hervé Dombret
    Pages 211-232
  14. Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

    • Deborah A. Thomas, Susan O’Brien, Stefan Faderl, Hagop Kantarjian
    Pages 233-255
  15. Molecular Therapies

    • Camille N. Abboud
    Pages 257-275
  16. Treatment of Relapsed Acute Lymphoblastic Leukemia

    • Daniel J. DeAngelo
    Pages 277-296

About this book

The current explosion of new areas of controversy in the treatment of acute lymphocytic leukemia in adults and young adults makes this comprehensive book a much needed reference for hematologists and oncologists. This book assembles leading authorities from around the globe to cover the full spectrum of ALL subtypes and their treatments. Specific topics of discussion include indications for allogeneic bone marrow transplant in first complete remission, the role of minimal residual disease in making treatment decisions, the treatment of young adults, and the treatment of Philadelphia chromosome positive ALL with the advent of the tyrosine kinase inhibitors. This is the first book to focus exclusively on the adult ALL patient. It provides a complete overview of diagnosis, molecular pathogenesis, evaluation, and treatment for this important patient population.

Reviews

From the reviews:

“The focus of this book is on acute lymphocytic leukemia in adults, with frequent allusions to the childhood form of disease. … the only recent text solely focused on acute lymphocytic leukemia as it relates to subtypes of disease in each of the adult age groups. It is up to date and well referenced, and it integrates basic, translational, and clinical science. As such it serves as a unique resource for scientists and clinicians in the field of acute lymphocytic leukemia.” (Paulette Mehta, Journal of the American Medical Association, June, 2011)

“Twenty-three chapters cover a range of clinically biased topics, from diagnosis and epidemiology to assessment of response to therapy, salvage protocols and the late effects of successful therapy. The text is broken up by tables, graphs and occasional colour illustrations, while extensive lists of references supplement each chapter. … A section on the biology of ALL helps to explain the diversity and underlying genetic instability of the disease. … this collection of reviews will prove to be a very useful supplementary reference text.” (Maria H. Gilleece, Bulletin of the Royal College of Pathologists, April, 2012)

Editors and Affiliations

  • Cleveland Clinic Foundation, Cleveland, USA

    Anjali S. Advani

  • School of Medicine, University Hospitals of Cleveland, Cleveland, USA

    Hillard M. Lazarus

Bibliographic Information

  • Book Title: Adult Acute Lymphocytic Leukemia

  • Book Subtitle: Biology and Treatment

  • Editors: Anjali S. Advani, Hillard M. Lazarus

  • Series Title: Contemporary Hematology

  • DOI: https://doi.org/10.1007/978-1-60761-707-5

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2011

  • Hardcover ISBN: 978-1-60761-706-8Published: 19 November 2010

  • Softcover ISBN: 978-1-4939-5766-8Published: 23 August 2016

  • eBook ISBN: 978-1-60761-707-5Published: 18 November 2010

  • Edition Number: 1

  • Number of Pages: XVI, 388

  • Topics: Hematology, Oncology

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access