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Lipoproteins in Diabetes Mellitus

  • Book
  • © 2014

Overview

Editors:
  1. Alicia J. Jenkins

    1. NHMRC Clinical Trials Centre, University of Sydney, Sydney, Australia

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    You can also search for this editor in PubMed   Google Scholar

  2. Peter P. Toth

    1. College of Medicine, University of Illinois, Peoria, USA

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    You can also search for this editor in PubMed   Google Scholar

  3. Timothy J. Lyons

    1. Section of Endocrinology and Diabetes Harold Hamm Diabetes Center, University of Oklahoma Health Sciences Center, Oklahoma City, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Authored by internationally well-respected scientists in the field
  • Arranged into two sections to readily access the required information
  • Describes and discusses recent major diabetes and lipid related clinical trials
  • Includes tables and figures to highlight major points
  • Includes supplementary material: sn.pub/extras

Part of the book series: Contemporary Diabetes (CDI)

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Table of contents (23 chapters)

  1. Front Matter

    Pages i-xiv
    Download chapter PDF

  2. Laboratory Assessment of Lipoproteins in Diabetes

    • David R. Sullivan, Barry Lewis
    Pages 1-10

  3. Lipoprotein Subclasses and Cardiovascular Disease Risk in Insulin-Resistant Diabetes

    • Michael Cobble, Patrick D. Mize, Eliot A. Brinton
    Pages 11-40

  4. Insulin Resistance and Atherosclerosis

    • Kamalpreet Singh, Vasudevan A. Raghavan
    Pages 41-54

  5. Apoproteins and Cell Surface Receptors Regulating Lipoprotein Metabolism in the Setting of Type 2 Diabetes

    • Thomas D. Dayspring
    Pages 55-99

  6. Lipoprotein Metabolism and Alterations Induced by Insulin Resistance and Diabetes

    • Gerald H. Tomkin, Daphne Owens
    Pages 101-124

  7. Production and Metabolism of Triglyceride-Rich Lipoproteins in Both the Normal and Diabetic States

    • Angela Pirillo, Giuseppe D. Norata, Alberico L. Catapano
    Pages 125-139

  8. Lipoprotein(a): Structure, Metabolism, and Pathophysiology

    • Alicia J. Jenkins, Karam M. Kostner, Gerhard M. Kostner
    Pages 141-155

  9. Lipoprotein Glycation in Diabetes Mellitus

    • Alicia J. Jenkins, Richard L. Klein, Andrzej S. Januszewski
    Pages 157-186

  10. Lipoprotein (LDL and HDL) Oxidation in Diabetes Mellitus

    • Marielle Kaplan, Michael Aviram, Tony Hayek
    Pages 187-201

  11. The Role of Modified Forms of LDL and Corresponding Autoantibodies in the Development of Complications in Diabetes

    • Maria F. Lopes-Virella, Gabriel Virella
    Pages 203-213

  12. Lipid: Extracellular Matrix Interactions as Therapeutic Targets in the Atherosclerosis of Diabetes

    • Narin Osman, Peter J. Little
    Pages 215-229

  13. Tools for Assessing Lipoprotein Metabolism in Diabetes Mellitus

    • Richard L. Klein
    Pages 231-238

  14. Endothelial Dysfunction and Dyslipidemia in Type 2 Diabetes: Pathogenesis, Significance and Therapy

    • Sandra J. Hamilton, Gerald F. Watts
    Pages 239-278

  15. Lipoproteins and Diabetic Nephropathy

    • Ville-Petteri Mäkinen, Nina Tolonen, Per-Henrik Groop
    Pages 279-299

  16. Roles of Extravasated and Modified Plasma Lipoproteins in Diabetic Retinopathy

    • Mingyuan Wu, Timothy J. Lyons
    Pages 301-313

  17. Effects of Lifestyle (Diet, Plant Sterols, Exercise) and Glycemic Control on Lipoproteins in Diabetes

    • Peter Clifton
    Pages 315-327

  18. About Randomised Clinical Trials Related to Lipoproteins in Diabetes Mellitus

    • Anthony Keech, Alicia J. Jenkins, Val Gebski
    Pages 329-346

  19. Statin Therapy: Impact on Dyslipidemia and Cardiovascular Events in Diabetic Patients

    • Seth S. Martin, Parag H. Joshi, Steven R. Jones
    Pages 347-355

  20. The PPAR System in Diabetes

    • Jean Claude Ansquer, Christelle Foucher
    Pages 357-372
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Keywords

About this book

Diabetes mellitus has become epidemic on a global scale, and millions of new cases are diagnosed every year. The epidemic of diabetes mellitus is expected to result in one of the steepest rises in human morbidity and mortality ever observed outside of wartime. Insulin resistance is a hallmark of pre-diabetes and type 2 diabetes mellitus, and is characterized by impaired insulin-signaling transduction. Authoritative and comprehensive, Lipoproteins in Diabetes Mellitus details the many changes wrought by insulin resistance and diabetes mellitus on lipid and lipoprotein metabolism. The book begins by summarizing the various techniques to measure lipoproteins and their subclasses. The mechanisms by which insulin resistance and diabetes mellitus increase risk for atherosclerosis, diabetic retinopathy, and diabetic nephropathy are then explored in detail. Finally, the effects of lifestyle modification and the results of clinical trials using established and investigational drugs are discussed.

An invaluable contribution to the literature, Lipoproteins in Diabetes Mellitus is a comprehensive reference on the clinical and scientific aspects of lipoproteins in diabetes. It will have a long-lasting and significant effect on the medical management of people with diabetes.

Editors and Affiliations

  • NHMRC Clinical Trials Centre, University of Sydney, Sydney, Australia

    Alicia J. Jenkins

  • College of Medicine, University of Illinois, Peoria, USA

    Peter P. Toth

  • Section of Endocrinology and Diabetes Harold Hamm Diabetes Center, University of Oklahoma Health Sciences Center, Oklahoma City, USA

    Timothy J. Lyons

About the editors

Alicia Jenkins, MBBS, MD, FRACP, FRCP
University of Oklahoma Health Sciences Center, Section of Endocrinology and Diabetes, Oklahoma City, OK, USA

Peter P. Toth, MD, PhD, FAAFP, FICA, FNLA, FCCP, FAHA, FACC
CGH Medical Center, Sterling, IL
University of Illinois College of Medicine, Clinical Family and Community Medicine, Peoria, IL
Michigan State University College of Osteopathic Medicine, Clinical Medicine, East Lansing, MI, USA

Timothy J. Lyons, MD, FRCP
University of Oklahoma Health Sciences Center, Section of Endocrinology and Diabetes, Harold Hamm Diabetes Center, Oklahoma City, OK, USA

Bibliographic Information

  • Book Title: Lipoproteins in Diabetes Mellitus

  • Editors: Alicia J. Jenkins, Peter P. Toth, Timothy J. Lyons

  • Series Title: Contemporary Diabetes

  • DOI: https://doi.org/10.1007/978-1-4614-7554-5

  • Publisher: Humana New York, NY

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media New York 2014

  • Hardcover ISBN: 978-1-4614-7553-8Published: 09 January 2014

  • eBook ISBN: 978-1-4614-7554-5Published: 08 January 2014

  • Series ISSN: 2197-7836

  • Series E-ISSN: 2197-7844

  • Edition Number: 1

  • Number of Pages: XIV, 466

  • Number of Illustrations: 36 b/w illustrations, 64 illustrations in colour

  • Topics: Endocrinology, Angiology, Cardiology

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