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Methods in Molecular Biology

Mitochondrial Medicine

Volume I, Probing Mitochondrial Function

Editors: Weissig, Volkmar, Edeas, Marvin (Eds.)

  • Includes cutting-edge methods and protocols for the assessment of mitochondrial function
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $109.00
price for USA (gross)
  • ISBN 978-1-4939-2257-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.00
price for USA
  • ISBN 978-1-4939-2256-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
price for USA
  • ISBN 978-1-4939-5572-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This expert volume covers an interdisciplinary and rapidly growing area of biomedical research comprising genetic, biochemical, pathological, and clinical studies aimed at the diagnosis and therapy of human diseases which are either caused by or associated with mitochondrial dysfunction. It dedicates itself to showcasing the tremendous efforts and the progress that has been made over the last decades in developing techniques and protocols for probing, imaging, and manipulating mitochondrial functions. Mitochondrial Medicine: Volume I, Probing Mitochondrial Function focuses on methods being used for the assessment of mitochondrial function under physiological conditions as well as in healthy isolated mitochondria. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Comprehensive and practical, Mitochondrial Medicine provides an essential source of know-how and inspiration to all researchers who are fascinated by this tiny organelle that seems so clearly to control the life and death of a single cell and whole organisms alike.

Table of contents (38 chapters)

  • Preparation of “Functional” Mitochondria: A Challenging Business

    Lehr, Stefan (et al.)

    Pages 1-8

  • Isolation and Quality Control of Functional Mitochondria

    Hartwig, Sonja (et al.)

    Pages 9-23

  • Isolation of Mitochondria-Associated ER Membranes (MAMs) and Glycosphingolipid-Enriched Microdomains (GEMs) from Brain Tissues and Neuronal Cells

    Annunziata, Ida (et al.)

    Pages 25-33

  • Fluorescence Analysis of Single Mitochondria with Nanofluidic Channels

    Pham, Ted (et al.)

    Pages 35-46

  • Optical Microwell Arrays for Large-Scale Studies of Single Mitochondria Metabolic Responses

    Vajrala, Venkata Suresh (et al.)

    Pages 47-58

Buy this book

eBook $109.00
price for USA (gross)
  • ISBN 978-1-4939-2257-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.00
price for USA
  • ISBN 978-1-4939-2256-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
price for USA
  • ISBN 978-1-4939-5572-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Mitochondrial Medicine
Book Subtitle
Volume I, Probing Mitochondrial Function
Editors
  • Volkmar Weissig
  • Marvin Edeas
Series Title
Methods in Molecular Biology
Series Volume
1264
Copyright
2015
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4939-2257-4
DOI
10.1007/978-1-4939-2257-4
Hardcover ISBN
978-1-4939-2256-7
Softcover ISBN
978-1-4939-5572-5
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XXV, 480
Number of Illustrations and Tables
42 b/w illustrations, 66 illustrations in colour
Topics