Methods in Molecular Biology

Chromosomal Mutagenesis

Editors: Pruett-Miller, Shondra M. (Ed.)

  • Includes all new cutting-edge methods and protocols for chromosomal mutagenesis research
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $109.00
price for USA (gross)
  • ISBN 978-1-4939-1862-1
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  • Immediate eBook download after purchase
Hardcover $139.00
price for USA
  • ISBN 978-1-4939-1861-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
price for USA
  • ISBN 978-1-4939-5541-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This new edition explores current and emerging mutagenesis methods focusing specifically on mammalian systems and commonly used model organisms through comprehensive coverage and detailed protocols. Since the first edition, major advances and discoveries have made chromosomal mutagenesis a widely used technique and one that is available to any molecular biology laboratory, and this collection provides detailed protocols, case-studies, and reviews from thought-leaders in the field. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and fully updated, Chromosomal Mutagenesis, Second Edition aims to help speed scientific discovery and aid in the next advances in the field.

Table of contents (19 chapters)

  • Genome Editing by Targeted Chromosomal Mutagenesis

    Carroll, Dana

    Pages 1-13

  • piggyBac Transposon-Based Insertional Mutagenesis in Mouse Haploid Embryonic Stem Cells

    Pettitt, Stephen J. (et al.)

    Pages 15-28

  • Using Phage Integrases in a Site-Specific Dual Integrase Cassette Exchange Strategy

    Geisinger, Jonathan M. (et al.)

    Pages 29-38

  • Therapeutic Genome Mutagenesis Using Synthetic Donor DNA and Triplex-Forming Molecules

    Reza, Faisal (et al.)

    Pages 39-73

  • Genome Engineering Using Adeno-Associated Virus (AAV)

    Howes, Rob (et al.)

    Pages 75-103

Buy this book

eBook $109.00
price for USA (gross)
  • ISBN 978-1-4939-1862-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.00
price for USA
  • ISBN 978-1-4939-1861-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
price for USA
  • ISBN 978-1-4939-5541-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Chromosomal Mutagenesis
Editors
  • Shondra M. Pruett-Miller
Series Title
Methods in Molecular Biology
Series Volume
1239
Copyright
2015
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4939-1862-1
DOI
10.1007/978-1-4939-1862-1
Hardcover ISBN
978-1-4939-1861-4
Softcover ISBN
978-1-4939-5541-1
Series ISSN
1064-3745
Edition Number
2
Number of Pages
XIV, 333
Number of Illustrations and Tables
22 illustrations in colour
Topics