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Neurobiological Studies of Addiction in Chronic Pain States

  • Book
  • © 2014

Overview

Editors:
  1. Carolyn A. Fairbanks

    1. Departments of Pharmaceutics, Pharmacology, Neuroscience, University of Minnesota, Minneapolis, USA

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  2. Thomas J. Martin, Ph.D.

    1. Pain Mechanisms Laboratory, Department of Anesthesiology, Wake Forest University Health Sciences, Winston-Salem, USA

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    You can also search for this editor in PubMed   Google Scholar

  • Focuses on methodological information important to the blend of chronic pain and addiction modeling
  • Explores current research on the specific brain regions and responses to opioids in subjects with chronic pain
  • Contains beneficial information on the clinical impact of prescription opioids

Part of the book series: Contemporary Clinical Neuroscience (CCNE, volume 17)

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Table of contents (8 chapters)

  1. Front Matter

    Pages i-xii
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  2. Introduction

    1. Front Matter

      Pages 1-1
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    2. Opioid and Non-Opioid Drug Responding Under States of Chronic Pain: A Timeline Spanning 1980 to Present Day

      • Carrie L. Wade, Carolyn A. Fairbanks
      Pages 3-14

  3. Basic Science

    1. Front Matter

      Pages 15-15
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    2. Opioid Self-Administration in the Presence of Chronic Pain: Analgesia or Addiction?

      • Eric E. Ewan, Thomas J. Martin
      Pages 17-30

    3. The Influence of Pain on Reward Processing: Current Literature and Prospects

      • Wiebke Gandhi, Susanne Becker, Petra Schweinhardt
      Pages 31-48

    4. Chronic Pain Stimuli Downregulate Mesolimbic Dopaminergic Transmission: Possible Mechanism of the Suppression of Opioid Reward

      • Minoru Narita, Keiichi Niikura, Akira Yamashita, Daigo Ikegami, Naoko Kuzumaki, Michiko Narita et al.
      Pages 49-58

  4. Methods

    1. Front Matter

      Pages 59-59
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    2. Drug Addiction and Chronic Pain: A Review of Animal Models

      • Carrie L. Wade, George F. Koob, Leandro F. Vendruscolo
      Pages 61-79

    3. Biopharmaceutical Considerations of Opioid Analgesics in Models of Self-Administration: Review and Summary

      • Carolyn A. Fairbanks, Cristina D. Peterson
      Pages 81-107

  5. Clinical Perspectives

    1. Front Matter

      Pages 109-109
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    2. Prenatal Exposure to Opioids

      • Lisa M. Schrott
      Pages 111-117

    3. Opioids in an Evidence-Based World

      • Scott A. Strassels
      Pages 119-127

  6. Back Matter

    Pages 129-132
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About this book

Using rodent models, this volume explores the basic neurobiology of the relationship among chronic pain, opioid pharmacology, and addiction.

Editors and Affiliations

  • Departments of Pharmaceutics, Pharmacology, Neuroscience, University of Minnesota, Minneapolis, USA

    Carolyn A. Fairbanks

  • Pain Mechanisms Laboratory, Department of Anesthesiology, Wake Forest University Health Sciences, Winston-Salem, USA

    Thomas J. Martin, Ph.D.

Bibliographic Information

  • Book Title: Neurobiological Studies of Addiction in Chronic Pain States

  • Editors: Carolyn A. Fairbanks, Thomas J. Martin, Ph.D.

  • Series Title: Contemporary Clinical Neuroscience

  • DOI: https://doi.org/10.1007/978-1-4939-1856-0

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media New York 2014

  • Hardcover ISBN: 978-1-4939-1855-3Published: 15 November 2014

  • Softcover ISBN: 978-1-4939-5183-3Published: 23 August 2016

  • eBook ISBN: 978-1-4939-1856-0Published: 14 November 2014

  • Series ISSN: 2627-535X

  • Series E-ISSN: 2627-5341

  • Edition Number: 1

  • Number of Pages: XII, 132

  • Number of Illustrations: 4 b/w illustrations, 3 illustrations in colour

  • Topics: Neurosciences, Pain Medicine, Animal Models

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