Editors:
- Includes cutting-edge techniques in using RNA interference for therapeutic purposes
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
- Includes supplementary material: sn.pub/extras
Part of the book series: Methods in Molecular Biology (MIMB, volume 1218)
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Table of contents (28 protocols)
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Front Matter
About this book
RNA Interference: Challenges and Therapeutic Opportunities provides readers with recent advances in siRNA design, delivery, targeting and methods to minimize siRNA’s unwanted effects. Preclinical and clinical use of synthetic siRNAs, the roles of miRNAs in cancer and the promise of extracellular miRNAs for diagnosis are also covered in this meticulous collection, along with novel methods for identifying endogenous siRNAs and the annotation of small RNA transcriptomes. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory.
Comprehensive and cutting-edge, RNA Interference: Challenges and Therapeutic Opportunities will aid researchers, clinicians, teachers and biotechnologists interested in the power of RNA-based therapies.Editors and Affiliations
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Institute for Cancer Research, Oslo University Hospital, Montebello, Norway
Mouldy Sioud
Bibliographic Information
Book Title: RNA Interference
Book Subtitle: Challenges and Therapeutic Opportunities
Editors: Mouldy Sioud
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-1538-5
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media New York 2015
Hardcover ISBN: 978-1-4939-1537-8Published: 15 October 2014
Softcover ISBN: 978-1-4939-4891-8Published: 22 September 2016
eBook ISBN: 978-1-4939-1538-5Published: 15 October 2014
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XVI, 495
Number of Illustrations: 50 b/w illustrations, 58 illustrations in colour
Topics: Pharmacology/Toxicology, Human Genetics