Methods in Molecular Biology

Mass Spectrometry Imaging of Small Molecules

Editors: He, Lin (Ed.)

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $89.00
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  • ISBN 978-1-4939-1357-2
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Hardcover $119.00
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  • ISBN 978-1-4939-1356-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $119.00
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  • ISBN 978-1-4939-5408-7
  • Free shipping for individuals worldwide
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About this book

Mass Spectroscopy Imaging (MSI) has emerged as an enabling technique to provide insight into the molecular entities within cells, tissues and whole-body samples and to understand inherent complexities within biological metabolomes. In Mass Spectrometry Imaging of Small Molecules: Methods and Protocols, experts in the MSI field present techniques for 2D and 3D visualization and quantification of a wide array of small molecular species present in biologically relevant samples. Chapters provide detailed operational instructions from sample preparation to method selection, from comparative quantification to structural identification and from data collection to visualization of small molecule mapping in complex samples. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols and notes on troubleshooting and avoiding known pitfalls.

Authoritative and easily accessible, Mass Spectrometry Imaging of Small Molecules: Methods and Protocols aims to bring the rapidly maturing methods of metabolic imaging to life science researchers and to minimize technical intimidation in adapting new technological platforms in biological research.

Reviews

“The purpose is to detail the rapidly maturing methods of metabolic imaging and to minimize technical challenges in adapting new technological platforms in biological research. These are quite worthy objectives that the book meets. The intended audience is life science researchers. The book also will be quite useful for students and scientists interested in learning more about mass spectrometry imaging of small molecules.” (Omer Iqbal, Doody’s Book Reviews, September, 2015)


Table of contents (19 chapters)

  • Current Status and Future Prospects of Mass Spectrometry Imaging of Small Molecules

    Brown, Victoria L. (et al.)

    Pages 1-7

  • Sample Preparation for 3D SIMS Chemical Imaging of Cells

    Winograd, Nicholas (et al.)

    Pages 9-19

  • TOF-SIMS Imaging of Lipids on Rat Brain Sections

    Touboul, David (et al.)

    Pages 21-27

  • MALDI-MS-Assisted Molecular Imaging of Metabolites in Legume Plants

    Gemperline, Erin (et al.)

    Pages 29-40

  • MALDI Mass Spectrometry Imaging of Lipids and Primary Metabolites on Rat Brain Sections

    Touboul, David (et al.)

    Pages 41-48

Buy this book

eBook $89.00
price for USA (gross)
  • ISBN 978-1-4939-1357-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $119.00
price for USA
  • ISBN 978-1-4939-1356-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $119.00
price for USA
  • ISBN 978-1-4939-5408-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Mass Spectrometry Imaging of Small Molecules
Editors
  • Lin He
Series Title
Methods in Molecular Biology
Series Volume
1203
Copyright
2015
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4939-1357-2
DOI
10.1007/978-1-4939-1357-2
Hardcover ISBN
978-1-4939-1356-5
Softcover ISBN
978-1-4939-5408-7
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 213
Number of Illustrations and Tables
13 b/w illustrations, 57 illustrations in colour
Topics