Synaptic Stress and Pathogenesis of Neuropsychiatric Disorders

Editors: Popoli, Maurizio, Diamond, David, Sanacora, Gerard (Eds.)

  • Outlines recent evidence of glutamate synapse change caused by stress
  • Discusses how the effects of stress can trigger or precipitate neuropsychiatric disorders
  • Brings together leading researchers in the field
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eBook $159.00
price for USA (gross)
  • ISBN 978-1-4939-1056-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $209.00
price for USA
  • ISBN 978-1-4939-1055-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $209.00
price for USA
  • ISBN 978-1-4939-4632-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Recent studies show that changes in Glutamate/GABA synapses and related pathways may determine whether the synaptic plasticity that occurs as a response to stress is adaptive or maladaptive. Findings have shed new light on the mechanisms that determine the effects of stress on cognitive and affective function. Researchers have brought a wide range of techniques to bear on the study of this problem, including cutting-edge live imaging techniques, electrophysiology, glutamate release from isolated live synaptic terminals, development of transgenic and animal models and new behavioral methods. This book provides an overview of these recent findings and of the techniques used as well as a discussion of how the molecular, cellular, and functional effects of stress may trigger or precipitate neuropsychiatric disorders such as depression, schizophrenia, anxiety and PTSD.

Reviews

From the book reviews:

“This informative book, written and edited by an international array of well-known stress researchers, provides the latest information on the molecular mechanisms mediating stress in the pathogenesis of neuropsychiatric illnesses. … The target audience includes bench neuroscientists and clinicians who want to learn about the latest research on fundamental neuroendocrine stress mechanisms and stress-related diseases. … Each chapter ends with relevant and timely citations of the scientific literature.” (Michael Joel Schrift, Doody’s Book Reviews, January, 2015)

Table of contents (17 chapters)

  • The Brain on Stress: The Good and the Bad

    McEwen, Bruce S.

    Pages 1-18

  • Regulation of Excitatory Synapses by Stress Hormones

    Joëls, Marian (et al.)

    Pages 19-32

  • Synaptic Stress, Changes in Glutamate Transmission and Circuitry, and Psychopathology

    Musazzi, Laura (et al.)

    Pages 33-52

  • Dual Regulation of Glutamatergic Transmission and Cognition by Stress in Prefrontal Cortex

    Zhen, Yan

    Pages 53-69

  • Role of Endocannabinoids in Regulating Glucocorticoid Effects on Memory for Emotionally Arousing Experiences

    Atsak, Piray (et al.)

    Pages 71-98

Buy this book

eBook $159.00
price for USA (gross)
  • ISBN 978-1-4939-1056-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $209.00
price for USA
  • ISBN 978-1-4939-1055-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $209.00
price for USA
  • ISBN 978-1-4939-4632-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Synaptic Stress and Pathogenesis of Neuropsychiatric Disorders
Editors
  • Maurizio Popoli
  • David Diamond
  • Gerard Sanacora
Copyright
2014
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4939-1056-4
DOI
10.1007/978-1-4939-1056-4
Hardcover ISBN
978-1-4939-1055-7
Softcover ISBN
978-1-4939-4632-7
Edition Number
1
Number of Pages
XIV, 355
Number of Illustrations and Tables
1 b/w illustrations, 48 illustrations in colour
Topics