Research and Development

Food Allergens

Biochemistry and Molecular Nutrition

Authors: Cirkovic Velickovic, Tanja, Gavrovic-Jankulovic, Marija

  • Identifies the components of foods that can influence food allergy development
  • Discusses 'molecular nutrition' as it relates to food allergies
  • Provides a detailed study of the most important and common food allergens
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  • ISBN 978-1-4939-0841-7
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Hardcover $129.00
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  • ISBN 978-1-4939-0840-0
  • Free shipping for individuals worldwide
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Softcover $129.00
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  • ISBN 978-1-4939-4559-7
  • Free shipping for individuals worldwide
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About this book

A food allergen has the ability to first elicit an IgE response, and then, on subsequent exposures, a clinical response to the same or similar protein. How harmless food protein becomes recognized by the mucosal immune system as an allergen remains an open question and more data are needed to explain how regulatory mechanisms of the mucosal immune system fail and result in allergic sensitization to dietary antigens.

Some biochemical characteristics associated with food allergens, such as the presence of multiple, linear IgE-binding epitopes and the resistance of the protein to digestion and processing, seem to predominate among food allergens. Digestion susceptibility of food allergens that sensitize via the gastrointestinal tract and stability to food processing conditions are inherently related to protein structural features. Thereby, physiological changes in the digestion process, pathological conditions affecting digestion, as well as procedures and food processing conditions that affect protein structure may all have a profound effect on the sensitizing potential and allergenicity of food proteins. In addition, signals coming from the diet and micro biome can modulate regulatory mechanisms of the mucosal immune system and influence mucosal immunity and intestinal barrier function.

The detection of allergenic ingredients in food products has received increased attention from the food industry and legislative and regulatory agencies over recent years. This has resulted in the improvement of applied safety measures that provide protection for food-allergic consumers and development of sensitive and highly specific analytical methods of food allergens detection. Food allergy is an important and common health issue and therefore there is a need to characterize the sensitizing potential of newly introduced proteins in genetically engineered foods. A combination of in vitro and in silico methods provide information that contributes to safety assessment. Suitable in vivo models may provide a more holistic assessment of allergenic potential of novel food proteins.

Table of contents (8 chapters)

  • Food Allergy and Gastrointestinal Tract

    Ćirković Veličković, Tanja (et al.)

    Pages 1-28

  • Intestinal Permeability and Transport of Food Antigens

    Ćirković Veličković, Tanja (et al.)

    Pages 29-56

  • Biochemistry and Molecular Biology of Food Allergens

    Ćirković Veličković, Tanja (et al.)

    Pages 57-76

  • Methods for Allergen Identification and Quantification in Food Matrices

    Ćirković Veličković, Tanja (et al.)

    Pages 77-93

  • Food Allergens Digestibility

    Ćirković Veličković, Tanja (et al.)

    Pages 95-140

Buy this book

eBook $99.00
price for USA (gross)
  • ISBN 978-1-4939-0841-7
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $129.00
price for USA
  • ISBN 978-1-4939-0840-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $129.00
price for USA
  • ISBN 978-1-4939-4559-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Food Allergens
Book Subtitle
Biochemistry and Molecular Nutrition
Authors
Series Title
Research and Development
Copyright
2014
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4939-0841-7
DOI
10.1007/978-1-4939-0841-7
Hardcover ISBN
978-1-4939-0840-0
Softcover ISBN
978-1-4939-4559-7
Edition Number
1
Number of Pages
XIII, 208
Number of Illustrations and Tables
10 b/w illustrations, 9 illustrations in colour
Topics