Methods in Molecular Biology

Pseudogenes

Functions and Protocols

Editors: Poliseno, Laura (Ed.)

  • Includes cutting-edge methods and protocols for the study of pseudogenes and the avoidance of inadvertent detection
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $89.00
price for USA (gross)
  • ISBN 978-1-4939-0835-6
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Hardcover $119.00
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  • ISBN 978-1-4939-0834-9
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Softcover $119.00
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  • ISBN 978-1-4939-4646-4
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About this book

Providing a list of methods useful both to those who wish to study pseudogenes and to those who actually want to avoid their inadvertent detection, Pseudogenes: Functions and Protocols explores techniques involving pseudogenic DNA, RNA, and peptides/proteins, once believed to lack any functionality, but now known to be involved in complex regulatory circuits. After a few introductory chapters that overview the functions so far attributed to pseudogenes, this thorough volume delves into methods for pseudogene identification, for the detection of pseudogene transcription and translation, and for the study of the functions of pseudogenic RNA and proteins, as well as methods to avoid pseudogene detection when the focus of the research is their highly homologous parental counterparts. As part of the highly successful Methods in Molecular Biology series, chapters feature the kind of detailed descriptions and implementation advice that ensures successful results in the lab.

Authoritative and practical, Pseudogenes: Functions and Protocols will contribute to the high interest of the scientific community toward pseudogenes, while stimulating the conception of pseudogene - centered research projects and providing experimental protocols that can facilitate their execution.

Table of contents (21 chapters)

  • Pseudogene Redux with New Biological Significance

    Salmena, Leonardo

    Pages 3-13

  • Contribution of Pseudogenes to Sequence Diversity

    Vihinen, Mauno

    Pages 15-24

  • Computational Methods for Pseudogene Annotation Based on Sequence Homology

    Harrison, Paul M.

    Pages 27-39

  • Computational Methods of Identification of Pseudogenes Based on Functionality: Entropy and GC Content

    Balakirev, Evgeniy S. (et al.)

    Pages 41-62

  • Methods of Identification of Pseudogenes Based on Functionality: Hybridization of 18S rRNA and mRNA During Translation

    Xing, Chuanhua

    Pages 63-73

Buy this book

eBook $89.00
price for USA (gross)
  • ISBN 978-1-4939-0835-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $119.00
price for USA
  • ISBN 978-1-4939-0834-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $119.00
price for USA
  • ISBN 978-1-4939-4646-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Pseudogenes
Book Subtitle
Functions and Protocols
Editors
  • Laura Poliseno
Series Title
Methods in Molecular Biology
Series Volume
1167
Copyright
2014
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4939-0835-6
DOI
10.1007/978-1-4939-0835-6
Hardcover ISBN
978-1-4939-0834-9
Softcover ISBN
978-1-4939-4646-4
Series ISSN
1064-3745
Edition Number
1
Number of Pages
X, 319
Number of Illustrations and Tables
20 b/w illustrations, 38 illustrations in colour
Topics