SpringerBriefs in Systems Biology

Next Generation Sequencing Technologies and Challenges in Sequence Assembly

Authors: El-Metwally, M.Sc, Sara, Ouda, Osama M., Helmy, Mohamed

  • Focuses on challenges in next generation sequencing technologies
  • Challenges include sequencing errors, expensive processing and memory usage and sequencer specific errors
  • This book provides overview on NGS methods, platforms and challenges and NGS sequence Assembly methods and challenges
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eBook $39.99
price for USA (gross)
  • ISBN 978-1-4939-0715-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $54.99
price for USA
  • ISBN 978-1-4939-0714-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The introduction of Next Generation Sequencing (NGS) technologies resulted in a major transformation in the way scientists extract genetic information from biological systems, revealing limitless insight about the genome, transcriptome and epigenome of any species. However, with NGS, came its own challenges that require continuous development in the sequencing technologies and bioinformatics analysis of the resultant raw data and assembly of the full length genome and transcriptome. Such developments lead to outstanding improvements of the performance and coverage of sequencing and improved quality for the assembled sequences, nevertheless, challenges such as sequencing errors, expensive processing and memory usage for assembly and sequencer specific errors remains major challenges in the field.

This book aims to provide brief overviews the NGS field with special focus on the challenges facing the NGS field, including information on different experimental platforms, assembly algorithms and software tools, assembly error correction approaches and the correlated challenges.

Table of contents (11 chapters)

  • Basics of Molecular Biology for Next-Generation Sequencing

    El-Metwally, Sara (et al.)

    Pages 3-13

  • Algorithms and Data Structures in Next-Generation Sequencing

    El-Metwally, Sara (et al.)

    Pages 15-26

  • First- and Next-Generations Sequencing Methods

    El-Metwally, Sara (et al.)

    Pages 29-36

  • Next-Generation Sequencing Platforms

    El-Metwally, Sara (et al.)

    Pages 37-44

  • Challenges in the Next-Generation Sequencing Field

    El-Metwally, Sara (et al.)

    Pages 45-49

Buy this book

eBook $39.99
price for USA (gross)
  • ISBN 978-1-4939-0715-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $54.99
price for USA
  • ISBN 978-1-4939-0714-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Next Generation Sequencing Technologies and Challenges in Sequence Assembly
Authors
Series Title
SpringerBriefs in Systems Biology
Series Volume
7
Copyright
2014
Publisher
Springer-Verlag New York
Copyright Holder
The Authors
eBook ISBN
978-1-4939-0715-1
DOI
10.1007/978-1-4939-0715-1
Softcover ISBN
978-1-4939-0714-4
Series ISSN
2193-4746
Edition Number
1
Number of Pages
XII, 118
Number of Illustrations and Tables
11 b/w illustrations, 1 illustrations in colour
Topics