Oxidative Stress in Applied Basic Research and Clinical Practice

Studies on Pediatric Disorders

Editors: Tsukahara, Hirokazu, Kaneko, Kazunari (Eds.)

  • Examines the basic science and clinical knowledge of the role of oxidative stress in the pathology of numerous pediatric disorders
  • Describes current diagnostic tools, laboratory methods and technology for treatment and prevention of pediatric disorders
  • Covers emerging technology and medical applications including discussions of biomarkers and antioxidants as therapeutic agents
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eBook $149.00
price for USA (gross)
  • ISBN 978-1-4939-0679-6
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  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-4939-0678-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-1-4939-4467-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This volume examines the role of oxidative stress in the pathology of numerous pediatric disorders. It covers a wide range of topics including the chemistry and biology of reactive oxygen species and nitric oxide, molecular biology of the enzymes generating these species, clinically useful biomarkers for evaluating oxidative stress status in humans, and the pathophysiology, clinical course and management of a variety of pediatric disorders, among others. The book also describes current diagnostic tools, laboratory methods and technology for treatment and prevention of pediatric disorders.  It explores emerging technology and medical applications including discussions of biomarkers and antioxidants as therapeutic agents.

Written by an international team of experts in both pediatrics and  free radical and antioxidant research, Studies on Pediatric Disorders is an invaluable addition to the Oxidative Stress in Applied Basic Research and Clinical Practice series.

About the authors

Hirokazu Tsukahara, MD, PhD graduated from the School of Medicine at Kyoto University, in Kyoto, Japan and obtained his PhD in medical science from Fukui Medical School, in Fukui, Japan. He is currently Associate Professor at the Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences. Dr. Tsukahara is a clinical scientist, specializing in the field of pediatrics and biological responses. He is the author or coauthor of more than 200 scientific papers and book chapters on general pediatrics, neonatology, endocrinology, metabolic diseases, infectious diseases, and cardiovascular diseases. His experimental research is focused on the chemistry and biology of nitric oxide, free radicals, and other bioactive mediators.

 

Kazunari Kaneko, MD, PhD graduated from the School of Medicine at Niigata University in Niigata, Japan and obtained his PhD in medical science from Juntendo University, in Tokyo. He is currently Professor and Chairman of the Department of Pediatrics at Kansai Medical University, Osaka, Japan. Dr. Kaneko is a pediatric nephrologist and a leading scientist in clinical studies, specializing in nephrotic syndrome and electrolyte disorders. He has also conducted basic research into the pathophysiological roles of nitric oxide and reactive oxygen species in diverse pediatric kidney diseases. He is currently a member of several regional and international societies including: Japan Pediatric Society (Councilor), Pediatric Nephrology (Executive board member), International Pediatric Nephrology Association, International Society of Nephrology, and American Society of Nephrology. He is on the editorial boards of several well-regarded medical journals, including International Journal of Nephrology, Clinical and Experimental Nephrology, and Journal of Pediatric Biochemistry.

Table of contents (27 chapters)

  • Oxygen and Oxidative Stress in the Newborn

    Saugstad, Ola Didrik

    Pages 3-13

  • Reactive Oxygen Species and Nitric Oxide in Vascular Function

    Wolin, Michael S.

    Pages 15-33

  • Nitrite-Dependent Nitric Oxide Production Pathway: Diversity of NO Production Systems

    Yamasaki, Hideo (et al.)

    Pages 35-54

  • Nitric Oxide and Endothelial Dysfunction

    Noiri, Eisei (et al.)

    Pages 55-69

  • Multifunctional Roles of Nitric Oxide (NO) in Neurons

    Katano, Tayo (et al.)

    Pages 71-84

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-4939-0679-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-4939-0678-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-1-4939-4467-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Studies on Pediatric Disorders
Editors
  • Hirokazu Tsukahara
  • Kazunari Kaneko
Series Title
Oxidative Stress in Applied Basic Research and Clinical Practice
Copyright
2014
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-4939-0679-6
DOI
10.1007/978-1-4939-0679-6
Hardcover ISBN
978-1-4939-0678-9
Softcover ISBN
978-1-4939-4467-5
Series ISSN
2197-7224
Edition Number
1
Number of Pages
XII, 494
Number of Illustrations and Tables
62 b/w illustrations, 53 illustrations in colour
Topics