Methods in Molecular Biology

The TNF Superfamily

Methods and Protocols

Editors: Bayry, Jagadeesh (Ed.)

  • Includes cutting-edge methods and protocols with a focus on TNF Superfamily members in health and disease
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $89.00
price for USA (gross)
  • ISBN 978-1-4939-0669-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $119.00
price for USA
  • ISBN 978-1-4939-0668-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $119.00
price for USA
  • ISBN 978-1-4939-5392-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Exploring these type II trans-membrane proteins, The TNF Superfamily: Methods and Protocols focuses on various techniques to investigate aspects of the TNF Superfamily members in health and disease. Opening with protocols to understand the signaling process of TNF family members, this detailed volume continues with technical examples of investigating the role of TNF family members in physiopathologies, protocols on modulation of TNF signaling by pathogens, experimental applications of TNF-reporter mice, as well as methodologies for various assays of TNF family members and the production of recombinant molecules.  Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.

Practical and ready to use, The TNF Superfamily: Methods and Protocols will aid researchers investigating this key family of proteins, involved in vital processes such as providing signals for activation, differentiation, survival and death of cells, modulation of immune response and inflammation, hematopoiesis and osteoclastogenesis.

Table of contents (18 chapters)

  • Assaying NF-κB Activation and Signaling from TNF Receptors

    Wu, Zhenzhen (et al.)

    Pages 1-14

  • Dissecting DR3 Signaling

    Pobezinskaya, Yelena L. (et al.)

    Pages 15-22

  • Modulation of FcεRI-Dependent Mast Cell Response by OX40L

    Sibilano, Riccardo (et al.)

    Pages 23-30

  • Analyzing the Signaling Capabilities of Soluble and Membrane TWEAK

    Trebing, Johannes (et al.)

    Pages 31-45

  • Regulation of Human Dendritic Cell Functions by Natural Anti-CD40 Antibodies

    Elluru, Sri Ramulu (et al.)

    Pages 47-54

Buy this book

eBook $89.00
price for USA (gross)
  • ISBN 978-1-4939-0669-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $119.00
price for USA
  • ISBN 978-1-4939-0668-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $119.00
price for USA
  • ISBN 978-1-4939-5392-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
The TNF Superfamily
Book Subtitle
Methods and Protocols
Editors
  • Jagadeesh Bayry
Series Title
Methods in Molecular Biology
Series Volume
1155
Copyright
2014
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4939-0669-7
DOI
10.1007/978-1-4939-0669-7
Hardcover ISBN
978-1-4939-0668-0
Softcover ISBN
978-1-4939-5392-9
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 226
Number of Illustrations and Tables
28 b/w illustrations, 15 illustrations in colour
Topics