Sunlight, Vitamin D and Skin Cancer

1. Front Matter

   Pages i-xxv

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2. Sunlight, Ultraviolet Radiation, Vitamin D and Skin Cancer

   • Michael F. Holick

   Pages 1-16

3. Vitamin D and Cancer

   • José Manuel Ordóñez, Hermann Brenner

   Pages 17-32

4. Vitamin D Status and Cancer Incidence and Ms

   • Irene Shui, Edward Giovannucci

   Pages 33-51

5. Solar Ultraviolet Irradiance and Cancer Incidence and Mortality

   • William B. Grant

   Pages 52-62

6. Vitamin D Receptor Polymorphisms and Cancer

   • Sara Gandini, Patrizia Gnagnarella, Davide Serrano, Elena Pasquali, Sara Raimondi

   Pages 69-105

7. The Role of Vitamin D for Cardiovascular Disease and Overall Mortality

   • Armin Zittermann, Sylvana Prokop

   Pages 106-119

8. Epidemiology of Skin Cancer

   • Ulrike Leiter, Thomas Eigentler, Claus Garbe

   Pages 120-140

9. Histology of Melanoma and Nonmelanoma Skin Cancer

   • Cornelia S. L. Müller

   Pages 141-159

10. Cytogenetics of Melanoma and Nonmelanoma Skin Cancer

    • Melanie A. Carless, Lyn R. Griffiths

    Pages 160-181

11. The Immune System and Skin Cancer

    • Sherry H. Yu, Jeremy S. Bordeaux, Elma D. Baron

    Pages 182-191

12. Human Papilloma Viruses and Skin Cancer

    • Sigrun Smola

    Pages 192-207

13. Ultraviolet Damage, DNA Repair and Vitamin D in Nonmelanoma Skin Cancer and in Malignant Melanoma

    • Jörg Reichrath, Knuth Rass

    Pages 208-233

14. Molecular Biology of Basal and Squamous Cell Carcinomas

    • Steffen Emmert, Michael P. Schön, Holger A. Haenssle

    Pages 234-252

15. Solar Ultraviolet Radiation, Vitamin D and Skin Cancer Surveillance in Organ Transplant Recipients (OTRS)

    • Jörg Reichrath

    Pages 253-271

16. Therapy of Metastatic Malignant Melanoma

    • Thomas Vogt

    Pages 272-281

17. The Vitamin D Receptor

    • Daniel D. Bikle

    Pages 282-302

18. Protection from Ultraviolet Damage and Photocarcinogenesis by Vitamin D Compounds

    • Clare Gordon-Thomson, Wannit Tongkao-on, Eric J. Song, Sally E. Carter, Katie M. Dixon, Rebecca S. Mason

    Pages 303-328

19. Interaction of Hedgehog and Vitamin D Signaling Pathways in Basal Cell Carcinomas

    • Benedikt Albert, Heidi Hahn

    Pages 329-341

20. Solar Ultraviolet Exposure and Mortality from Skin Tumors

    • Marianne Berwick, Claire Pestak, Nancy Thomas

    Pages 342-358

The goal of this volume is to comprehensively cover a highly readable, updated and extended, overview on our present knowledge of positive and negative effects of UV‑exposure, with a focus on vitamin D and skin cancer. Topics that are discussed in‑depth by leading researchers and clinicians range from the newest findings in endocrinology, epidemiology, histology, photobiology, immunology, cytogenetics and molecular pathology to new concepts for prophylaxis and treatment. Experts in the field as well as health care professionals not intimately involved in these specialized areas are provided with the most significant and timely information related to these topics. It is the aim of the second edition of this book to summarize essential up‑to‑date information for every clinician or scientist interested in how to balance between positive and negative effects of UV‑exposure to minimize the risks of developing vitamin D deficiency and skin cancer.

• UV-exposure
• UV-radiation
• melanoma
• prophylaxis
• vitamin D deficiency

• Clinic for Dermatology Venerology and Allergology, The Saarland University Hospital, Homburg, Germany

  Jörg Reichrath

Jörg Reichrath is Professor for Dermatology and Deputy Director of the Clinic for Dermatology, Allergology and Venerology at the Saarland University Hospital in Homburg/Saar, Germany. Main research interests include photobiology, dermato‑endocrinology and dermato‑oncology. He is a member of numerous national and international scientific organizations, including the German Dermatological Society (DDG), the Deutsche Krebsgesellschaft (DKG), and the German Dermatologic Co‑operative Oncology Group (DeCOG). He has been awarded numerous prizes including the Arnold Rikli-Prize 2006. Jörg Reichrath received his academic degrees (Dr. med., venia legendi) from the Saarland University, Germany.

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