Tumor-Induced Immune Suppression

Mechanisms and Therapeutic Reversal

Editors: Gabrilovich, Dmitry I., Hurwitz, Arthur A. (Eds.)

  • Features extensive updates to the original edition and several new chapters
  • Presents a comprehensive overview of different mechanisms of immune dysfunction
  • Discusses a number of new mechanisms that have never been discussed in a monograph report including: T-cell inhibitory molecules and regulatory tolergenic DCs
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eBook $189.00
price for USA (gross)
  • ISBN 978-1-4899-8056-4
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $239.00
price for USA
  • ISBN 978-1-4899-8055-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $239.00
price for USA
  • ISBN 978-1-4939-5051-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Tumor-Induced Immune Suppression - Prospects and Progress in Mechanisms and Therapeutic Reversal presents a comprehensive overview of large number of different mechanisms of immune dysfunction in cancer and therapeutic approaches to their correction. This includes the number of novel mechanisms that has never before been discussed in previous monographs.

The last decades were characterized by substantial progress in the understanding of the role of the immune system in tumor progression. Researchers have learned how to manipulate the immune system to generate tumor specific immune response, which raises high expectations for immunotherapy to provide breakthroughs in cancer treatment. It is increasingly clear that tumor-induced abnormalities in the immune system not only hampers natural tumor immune surveillance, but also limits the effect of cancer immunotherapy. Therefore, it is critically important to understand the mechanisms of tumor-induced immune suppression to make any progress in the field and this monograph provides these important insights.

Table of contents (16 chapters)

  • Regulatory T Cells and Cancer

    Turk, Mary Jo

    Pages 1-36

  • Th17 Cells in Cancer

    Paulos, Chrystal M. (et al.)

    Pages 37-75

  • Mast Cells and Immune Response in Cancer

    Colombo, Mario P. (et al.)

    Pages 77-98

  • Myeloid-Derived Suppressor Cells in Tumor-Induced T Cell Suppression and Tolerance

    Serafini, Paolo (et al.)

    Pages 99-150

  • Immunobiology of Dendritic Cells in Cancer

    Shurin, Michael R. (et al.)

    Pages 151-184

Buy this book

eBook $189.00
price for USA (gross)
  • ISBN 978-1-4899-8056-4
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $239.00
price for USA
  • ISBN 978-1-4899-8055-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $239.00
price for USA
  • ISBN 978-1-4939-5051-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Tumor-Induced Immune Suppression
Book Subtitle
Mechanisms and Therapeutic Reversal
Editors
  • Dmitry I. Gabrilovich
  • Arthur A. Hurwitz
Copyright
2014
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-4899-8056-4
DOI
10.1007/978-1-4899-8056-4
Hardcover ISBN
978-1-4899-8055-7
Softcover ISBN
978-1-4939-5051-5
Edition Number
2
Number of Pages
XIV, 464
Number of Illustrations and Tables
4 b/w illustrations, 34 illustrations in colour
Topics