Application of Near Infrared Spectroscopy in Biomedicine

1. Front Matter

   Pages i-ix

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2. Principles and Instrumentation

   • Yutaka Yamashita, Masatsugu Niwayama

   Pages 1-19

3. Photon Migration in Tissue

   • Masatsugu Niwayama, Yutaka Yamashita

   Pages 21-35

4. Photon Migration in NIRS Brain Imaging

   • Eiji Okada

   Pages 37-58

5. Clinical Application of NIRS

   • Miura Hajime

   Pages 59-74

6. In-Vivo NIRS and Muscle Oxidative Metabolism

   • Takafumi Hamaoka

   Pages 75-91

7. Intracellular Oxygen Dynamics Observed by NIRS During Skeletal Muscle Contraction

   • Kazumi Masuda

   Pages 93-108

8. Muscle Oxygen Saturation Measurements in Diving Mammals and Birds Using NIRS

   • Cassondra L. Williams, Paul J. Ponganis

   Pages 109-121

9. Noninvasive NMR and NIRS Measurement of Vascular and Intracellular Oxygenation In Vivo

   • Youngran Chung, Thomas Jue

   Pages 123-137

10. Problem Solutions

    • Thomas Jue, Kazumi Masuda

    Pages 139-145

11. Clinical Application of NIRS

    • Miura Hajime

    Pages E1-E1

12. Back Matter

    Pages 147-151

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In keeping with the style of the Handbook of Modern Biophysics, this fourth volume, Application of Near-Infrared Spectroscopy in Biomedicine, balances the need for physical science/mathematics formalism with a demand for biomedical perspectives. Each chapter divides the presentation into two major parts: the first establishes the conceptual framework and describes the instrumentation or technique, while the second illustrates current applications in addressing complex biology questions. With the additional sections on further reading, problems, and references, the interested reader can explore some chapter ideas more widely.

• BIOCHEMISTRY & MOLECULAR MEDICINE, University of California Davis BIOCHEMISTRY & MOLECULAR MEDICINE, Davis, USA

  Thomas Jue

• Kanazawa University, Kanazawa, Japan

  Kazumi Masuda

Thomas Jue is a Professor in the Department of Biochemistry and Molecular Medicine at the University of California Davis. He is an internationally recognized expert in developing and applying magnetic resonance techniques to study animal as well as human physiology in vivo and has published extensively in the field of magnetic resonance spectroscopy and imaging, near-infrared spectroscopy, bioenergetics, cardiovascular regu-lation, exercise, and marine biology. As the Chair of the Biophysics Graduate Group Program at University of California Davis, he launched an initiative to establish a biophysics book series that will balance the physical-science/mathematics formalism with the biomedical perspective in order to develop an attractive education curriculum at the interface of physical science, engineering, mathematics, biology, and medicine. The Handbook of Modern Biophysics represents part of that curriculum development effort.

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