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Bone Drugs in Pediatrics

Efficacy and Challenges

Editors: Klein, Gordon (Ed.)

  • Presents evidence for the use of certain drugs in the treatment and prevention of bone loss in children
  • Balances the pros and cons of utilizing these drugs in the pediatric population
  • Highlights the potential for future use of these and other drugs with children
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eBook $109.00
price for USA (gross)
  • ISBN 978-1-4899-7436-5
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  • Immediate eBook download after purchase
Hardcover $139.00
price for USA
  • ISBN 978-1-4899-7435-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
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  • ISBN 978-1-4899-7848-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Rent the ebook  
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About this book

Bone Drugs in Pediatrics brings together in one place the evidence for the use of certain drugs in the treatment and prevention of bone loss in children, as well as the reservations still present in the pediatric community regarding their use. Beginning with a discussion of developmental pharmacokinetics and drug development for pediatric diseases where bone loss occurs, such as osteogenesis imperfecta, the physiology of pediatric bone and how best to monitor the safety and efficacy of these drugs is presented. The pros and cons of utilizing the drugs themselves – such as bisphosphonates, antiresorptives and anabolic agents – within the pediatric population are carefully considered, with an eye toward safe and effective integration. The potential use of drugs in future treatment is also highlighted. On the whole, Bone Drugs in Pediatrics is a cogent presentation of the ongoing debate surrounding the potential for pharmacological interventions in pediatric bone loss.

About the authors

Gordon L. Klein, MD, MPH, Department of Orthopaedic Surgery, University of Texas Medical Branch, Galveston, TX, USA.

Table of contents (13 chapters)

  • Introduction

    Klein, Gordon L.

    Pages 1-3

  • Developmental Pharmacokinetics: Drug Disposition Relative to Age

    Reed, Michael D. (et al.)

    Pages 5-22

  • Drug Development for Pediatric Diseases with Bone Loss

    Zhang, Chi

    Pages 23-36

  • Paediatric Bone Physiology and Monitoring the Safety and Efficacy of Bone Drugs in Children

    Logan, John G. (et al.)

    Pages 37-65

  • Bisphosphonates in Osteogenesis Imperfecta

    Biggin, Andrew (et al.)

    Pages 67-80

Buy this book

eBook $109.00
price for USA (gross)
  • ISBN 978-1-4899-7436-5
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.00
price for USA
  • ISBN 978-1-4899-7435-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
price for USA
  • ISBN 978-1-4899-7848-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Rent the ebook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
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Bibliographic Information

Bibliographic Information
Book Title
Bone Drugs in Pediatrics
Book Subtitle
Efficacy and Challenges
Editors
  • Gordon Klein
Copyright
2014
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4899-7436-5
DOI
10.1007/978-1-4899-7436-5
Hardcover ISBN
978-1-4899-7435-8
Softcover ISBN
978-1-4899-7848-6
Edition Number
1
Number of Pages
XIII, 233
Number of Illustrations and Tables
17 b/w illustrations, 28 illustrations in colour
Topics