Epilepsy and the Corpus Callosum 2

1. Front Matter

   Pages i-xv

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2. Corpus Callosum Organization and Development

   1. Front Matter

      Pages N1-N1

      PDF

   2. Corpus Callosum: History

      • Mitchell Glickstein

      Pages 1-10

   3. Development of the Corpus Callosum

      • Herbert P. Killackey

      Pages 11-13

   4. The Organization of Callosal Connections in Primates

      • Jon H. Kaas

      Pages 15-27

   5. Organization and Development of Interhemispheric Connections of the Prefrontal Cortex in Rhesus Monkey

      • Michael L. Schwartz

      Pages 29-47

   6. Ontogeny of Visual Callosal Projections in Primates

      • Henry Kennedy, Colette Dehay

      Pages 49-57

   7. Experimental Manipulations of the Organization of Interhemispheric Projections

      • Robert Rhoades

      Pages 59-60

3. Experimental Epilepsy

   1. Front Matter

      Pages N2-N2

      PDF

   2. Midline Subcortical Structures for Transhemispheric Ictal and Interictal Transmission

      • Juhn A. Wada

      Pages 61-78

   3. Forebrain Commissures and Limbic Kindling

      • Dan C. McIntyre

      Pages 79-89

   4. Callosal and Thalamic Transection: Effects on Spontaneous and Pentylenetetrazol-Induced Absence Seizures in Rats

      • M. Vergnes, C. Marescaux

      Pages 91-96

   5. Role of the Corpus Callosum in the Photosensitive Epilepsy of Baboons

      • Ch. Menini, C. Silva-Barrat, H. Fukuda, R. Naquet, J. Wada

      Pages 97-106

4. Clinical Epilepsy

   1. Front Matter

      Pages N3-N3

      PDF

   2. Some Historical Aspects of Callosotomy for Epilepsy

      • Joseph E. Bogen

      Pages 107-121

   3. Corpus Callosum Section: Preoperative Evaluation

      • Peter D. Williamson

      Pages 123-135

   4. EEG Selection for Corpus Callosotomy

      • John R. Gates

      Pages 137-144

   5. Seizure Types: Results of Partial and Complete Callosotomy in Adults

      • Susan S. Spencer, Dennis D. Spencer

      Pages 145-152

   6. Functional Pathways Underlying Ipsilateral and Contralateral Spread of Temporal Lobe Seizures

      • Charles L. Wilson

      Pages 153-173

   7. Corpus Callosum Section for Complex Partial Seizures

      • S. J. Purves, J. A. Wada, W. B. Woodhurst

      Pages 175-182

In August of 1991, a second Dartmouth International Workshop on the corpus callosum was convened to share and discuss the progress that had been made over the decade that had passed following the first workshop. A nucleus of basic and clinical scientists came together to discuss their work and the work of others in a field that has been broadened clinically by the addition of many new centers throughout the world that are now performing corpus callosotomy for intractable epilepsy. This text was stimulated by the participants' presentations and associated fertile discussions. It is compiled from the conference and subsequent studies. It reflects, both at the basic and clinical level, an important and expanding field of neural science endeavor. In keeping with the present and rapidly expanding field of outcomes assessment, callosotomy is again evaluated in light of a further decade of surgery and follow-up. Callosotomy continues to be a useful, palliative procedure and the indications for its use have been better established. The basic science section is a supplement to the first edition and elaborates progress in both new data and ideas. The section on experimental epilepsy models adds further support to the clinical rationale for callosotomy. Perhaps of greater importance is the contribution of experimental models to our understanding of the propagation of seizure activity. The section on the neuropsychology of the split brain patient demonstrates the continuing major contributions to the understanding of brain and behavior that pour forth from this cornucopia.

• behavior
• brain
• cortex
• electroencephalography (EEG)
• epilepsy
• forebrain
• neuropsychology
• psychology
• surgery

• Section of Neurology, Dartmouth-Hitchcock Medical Center, Lebanon, USA

  Alexander G. Reeves, David W. Roberts

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