Advances in Behavioral Biology

Novel Approaches to the Treatment of Alzheimer’s Disease

Editors: Meyer, E. (Ed.)

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About this book

Alzheimer's disease afflicts up to 1 in 5 people over the age of 65 years and causes untold suffering of the patient and their family. The cause of this disease is unknown; indeed, evidence increasingly suggests that there may be multiple Alzheimer-type syndromes with different etiologies, analogous to different types of psychosis. Currently there are no means to prevent the disease, slow its progress or reverse its neurodegenerative consequences. With few exceptions, clinical trials of a variety of compounds have resulted in patient responses that are disappointing with respect to both the proportion of responders and the magnitude of the responses. Novel approaches to the treatment of Alzheimer's disease are clearly warranted. For this reason, we organized the First Suncoast Workshop on the Neurobiology of Aging in St. Petersburg, Florida, which took place from February 26-March 1, 1989. This workshop focused on novel treatments and models for Alzheimer's disease and represented a cooperative venture among academia, government and industry, both in its participants and sponsorship. The Center for the Neurobiology of Aging at the University of Florida, the National Institute on Aging and Taiho Pharmaceutical Corporation in Japan sponsored the workshop in which scientists from the North America, Europe, Japan and other parts of Asia participated.

Table of contents (31 chapters)

  • A Functionalized Congener Approach to Muscarinic Ligands

    Jacobson, Kenneth A. (et al.)

    Pages 1-9

  • AF102B: A Novel M1 Agonist as a Rational Treatment Strategy in Alzheimer’s Disease

    Fisher, Abraham (et al.)

    Pages 11-16

  • Muscarinic Receptors, Phosphoinositide Hydrolysis, and Neuronal Plasticity in the Hippocampus

    Crews, Fulton T. (et al.)

    Pages 17-24

  • Effects of Cholinergic Drugs on Extracellular Levels of Acetylcholine and Choline in Rat Cortex, Hippocampus and Striatum Studied by Brain Dialysis

    Toide, Katsuo (et al.)

    Pages 25-38

  • Delayed Matching-to-Sample in Monkeys as a Model for Learning and Memory Deficits: Role of Brain Nicotinic Receptors

    Jackson, William J. (et al.)

    Pages 39-52

Buy this book

eBook $89.00
price for USA (gross)
  • ISBN 978-1-4684-5727-8
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $119.00
price for USA
  • ISBN 978-1-4684-5729-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Novel Approaches to the Treatment of Alzheimer’s Disease
Editors
  • E. Meyer
Series Title
Advances in Behavioral Biology
Series Volume
36
Copyright
1989
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4684-5727-8
DOI
10.1007/978-1-4684-5727-8
Softcover ISBN
978-1-4684-5729-2
Series ISSN
0099-6246
Edition Number
1
Number of Pages
XIV, 386
Number of Illustrations and Tables
137 b/w illustrations
Topics