Nato ASI Series

DNA-Ligand Interactions

From Drugs to Proteins

Editors: Guschlbauer, W. (Ed.)

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About this book

This volume contains the texts of the nineteen lectures presented at the NATO-ASI - FEBS Course on "DNA - ligand interactions: from drugs to proteins." The Advanced Study Institute (ASIl was held from August 30th to September 11th. 1986 in the Abbey of Fontevraud (France). The ASI was attended by 112 participants from a wide scientific horizon and from twentyone different countries. It was in some way a follow-up of the ASI held in Maratea. Italy in May 1981 and which was published in the NATO ASI Life Science series as volume 45. While much has been learned about the way the cellular machinery maintains and transmits the genetic heritage. as well as how these processes are regulated. little is Known about how the interactions between the various partners involved are taKing place. The interactions of drugs and proteins with nucleic acids are of evident importance in the understanding of these problems. The spectacular advances in recombinant DNA technology and the increased sophistication of biophysical techniques. in particular >:-ray diffraction and nuclear magnetic resonance. have created a scientific environment which is highly promising for the future of research in molecular biology. These advances permH the serious hope that biology on the molecular level may become a r-eality. Some of the contributions at the ASI presented the most recent advances in this e>:citing field.

Table of contents (20 chapters)

  • DNA Structure: Current Results from Single Crystal X-Ray Diffraction Studies

    Kennard, Olga

    Pages 1-21

  • One- and Two-Dimensional NMR Studies of the Structures of Simple Sequence DNAs

    Kearns, David R.

    Pages 23-43

  • The Major and Minor Grooves of the DNA Helix as Conduits for Information Transfer

    Dickerson, Richard E. (et al.)

    Pages 45-62

  • Unusual DNA Structures and Gene Regulation

    Wells, Robert D.

    Pages 63-83

  • Specificity and Dynamics of Protein-Nucleic Acid Interactions

    Porschke, Dietmar

    Pages 85-104

Buy this book

eBook $74.99
price for USA (gross)
  • ISBN 978-1-4684-5383-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $99.00
price for USA
  • ISBN 978-1-4684-5385-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
DNA-Ligand Interactions
Book Subtitle
From Drugs to Proteins
Editors
  • W. Guschlbauer
Series Title
Nato ASI Series
Series Volume
137
Copyright
1987
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4684-5383-6
DOI
10.1007/978-1-4684-5383-6
Softcover ISBN
978-1-4684-5385-0
Edition Number
1
Number of Pages
X, 290
Topics