Cellular Senescence and Somatic Cell Genetics

Senescence

Dominant or Recessive in Somatic Cell Crosses?

Editors: Nichols, Warren (Ed.)

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eBook $89.00
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  • ISBN 978-1-4684-2508-6
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Softcover $119.00
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About this book

This monograph, Senescence; Dominant or Recessive In Somatic Cell Crosses? represents the second annual workshop to promote theory and concept development in aging research. These workshops are part of a resource to bank cultured cells of special interest to aging research that was established at the Institute for Medical Research in Camden. New Jersey. by the National Institute on Aging in 1974. The underlying theme of the workshops is the use of cultured cells in a variety of somatic cell genetic systems designed to define mechanisms of in vitra cellular scen­ escence and the possible insights that this may provide to the problems of in viva aging. The concept also includes bringing together workers from a variety of disciplines to stimulate new and innovative thoughts and work in the area. The current work­ shop focuses on the relative role of nucleus and cytoplasm on determining the in vitra lifespan of human diploid cells as well as the relative influence of old and young cells when combined within a single cell structure. The techniques and procedures discussed should make significant contributions to understanding in vitra senescence and may lead to the mapping of an area or areas of the genome linked to senescence as is being accomplished with viral transformation of normal cells. Warren W. Nichols Donald G. Murphy ~i Contents Theoretic Mechanisms of in vitpo Senescence 1 F. MaPott Sinex . . . . . . . . . . . . Senescence in Ce1l Cu1ture: An Accumu1ation of Errors or Terminal Differentiation? 13 Vincent J. GPistofaZo . . . . . . . . . . . . . .

Table of contents (10 chapters)

  • Theoretical Mechanisms of in Vitro Senescence

    Sinex, F. Marott

    Pages 1-11

  • Senescence in Cell Culture: An Accumulation of Errors or Terminal Differentiation?

    Cristofalo, Vincent J.

    Pages 13-21

  • Synkaryon and Heterokaryon Analyses of Clonal Senescence

    Norwood, Thomas H. (et al.)

    Pages 23-38

  • Comments about the Paper by Norwood et al. and an Idea Relating Somatic Cell Mutations to Cellular Senescence

    DeMars, Robert

    Pages 39-55

  • Fusion of Cytoplasts and Karyoplasts and How This Pertains to Research of Aging and Transformation

    Muggleton-Harris, Audrey L.

    Pages 57-72

Buy this book

eBook $89.00
price for USA (gross)
  • ISBN 978-1-4684-2508-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $119.00
price for USA
  • ISBN 978-1-4684-2510-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Senescence
Book Subtitle
Dominant or Recessive in Somatic Cell Crosses?
Editors
  • Warren Nichols
Series Title
Cellular Senescence and Somatic Cell Genetics
Copyright
1977
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4684-2508-6
DOI
10.1007/978-1-4684-2508-6
Softcover ISBN
978-1-4684-2510-9
Edition Number
1
Number of Pages
X, 124
Number of Illustrations and Tables
8 b/w illustrations
Topics