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Neurobiology of Aging

An Interdisciplinary Life-Span Approach

  • Book
  • © 1975

Overview

Editors:
  1. J. Mark Ordy

    1. Department of Neurobiology Delta Regional Primate Research Center, Tulane University, Covington, USA

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  2. Kenneth R. Brizzee

    1. Division of Biomedical Sciences, Delta Regional Primate Research Center, Covington, USA
      Department of Anatomy, Tulane University School of Medicine, New Orleans, USA

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Advances in Behavioral Biology (ABBI, volume 16)

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Table of contents (25 chapters)

  1. Front Matter

    Pages i-ix
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  2. Definitions, theories, methods, molecular, cellular, organ and species difference in aging

    1. Principles of Mammalian Aging

      • J. Mark Ordy
      Pages 1-22

    2. Role of the Nervous System in Aging — Correlations Among Life Span, Brain-Body Weight and Metabolism

      • W. Jay Hansche
      Pages 23-35

    3. Relation of Development and Aging; Pre- and Postnatal Differentiation of the Brain as Related to Aging

      • O. A. Schjeide
      Pages 37-83

  3. Psychophysiological changes in aging

    1. The Nervous System, Behavior and Aging: An Interdisciplinary Life-Span Approach

      • J. Mark Ordy
      Pages 85-118

    2. Sensory Processes in Man During Maturity and Senescence

      • John F. Corso
      Pages 119-143

    3. Changes in Learning and Memory During Aging

      • Paul E. Gold, James L. McGaugh
      Pages 145-158

    4. Two Efferent Systems: Potential for Late-Life Changes

      • Jack D. Maser
      Pages 159-173

  4. Neurophysiological changes in the nervous system in aging

    1. Life Span Changes in the Electrical Activity of the Human Brain as Reflected in the Cerebral Evoked Response

      • E. C. Beck, R. E. Dustman, T. Schenkenberg
      Pages 175-192

    2. Changes in Neuromuscular Relationships in Aging

      • E. Gutmann, V. Hanzlikova
      Pages 193-207

    3. Changes in Limbic, Neuroendocrine and Autonomic Systems, Adaptation Homeostasis During Aging

      • Bernice Kaack, J. Mark Ordy, Bruce Trapp
      Pages 209-231

    4. Autoimmunity and Aging of the Nervous System

      • R. W. Lang, D. J. Carlo
      Pages 233-251

  5. Neurochemical changes in the nervous system in aging

    1. Neurochemical Changes in Composition, Metabolism and Neurotransmitters in the Human Brain with Age

      • J. Mark Ordy, Bernice Kaack
      Pages 253-285

    2. Age Changes in the Human for Some Enzymes Associated with Metabolism of Catecholamines, GABA and Acetylcholine

      • E. G. McGeer, P. L. McGeer
      Pages 287-305

    3. Age-Related Changes in Nucleic Acids and Protein Synthesis

      • R. L. Herrmann
      Pages 307-327

    4. Neurochemistry of the Developing and Aging Mammalian Brain

      • J. M. Davis, W. A. Himwich
      Pages 329-357

    5. Changes in Brain Lipids During Aging

      • L. A. Horrocks, G. Y. Sun, Robert A. D’Amato
      Pages 359-367

    6. Age Pigment, A Biochemical Indicator of Intracellular Aging

      • A. N. Siakotos, D. Armstrong
      Pages 369-399

  6. Morphological changes in the nervous system in aging

    1. Gross Morphometric Analyses and Quantitative Histology of the Aging Brain

      • Kenneth R. Brizzee
      Pages 401-423

    2. Changes in Microanatomy, Neurocytology and Fine Structure with Aging

      • Kenneth R. Brizzee, P. Klara, J. E. Johnson
      Pages 425-461
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Keywords

About this book

Aging is one of the most universal and inevitable social and sci­ entific challenges confronting man. The lives of all multicellular organisms begin with conception, extend through phases of development, maturity, senescence and finally end in death. Man is no exception, but has the unique feature of a complex brain. It plays an integra­ tive role in adaptation to the physical and social environments through reflexes, conditioning and more complex forms of learning. The brain is a repository for both inherited and acquired information. With the development of speech and the formation of symbolic language, the human brain has made it possible to transmit information cultur­ ally (horizontal) to other members of society, in addition to genetic (vertical) transmission to progeny. This horizontal transmission, which has reached its highest form in man, is a powerful extension of genetic transmission. The brain may provide man all that is of im­ portance in life. It has played a key role in the evolution of life by maintaining and extending the life span. Many mental or intellectual capacities of man reach a peak in early adulthood, remain relatively constant throughout maturity and then appear to decline during senescence. Behaviorally, there appears to be a decrease in sensory, learning and motor functions with aging in all mammalian species. As integrated adaptive control systems, the brain and neuroendocrines have been closely associated with the homeostatic adaptation to environmental challenges throughout .the life span.

Editors and Affiliations

  • Department of Neurobiology Delta Regional Primate Research Center, Tulane University, Covington, USA

    J. Mark Ordy

  • Division of Biomedical Sciences, Delta Regional Primate Research Center, Covington, USA

    Kenneth R. Brizzee

  • Department of Anatomy, Tulane University School of Medicine, New Orleans, USA

    Kenneth R. Brizzee

Bibliographic Information

  • Book Title: Neurobiology of Aging

  • Book Subtitle: An Interdisciplinary Life-Span Approach

  • Editors: J. Mark Ordy, Kenneth R. Brizzee

  • Series Title: Advances in Behavioral Biology

  • DOI: https://doi.org/10.1007/978-1-4684-0925-3

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Plenum Press, New York 1975

  • Softcover ISBN: 978-1-4684-0927-7Published: 25 November 2012

  • eBook ISBN: 978-1-4684-0925-3Published: 29 June 2013

  • Series ISSN: 0099-6246

  • Edition Number: 1

  • Number of Pages: IX, 603

  • Topics: Public Health

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