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Treatment of EARLY DIABETES

  • Book
  • © 1979

Overview

Editors:
  1. Rafael A. Camerini-Davalos

    1. Diabetes Center, New York Medical College, New York, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Bernard Hanover

    1. Diabetes Center, New York Medical College, New York, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 119)

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Table of contents (76 chapters)

  1. Front Matter

    Pages i-xvi
    Download chapter PDF

  2. Early Diabetes: Definition, Present Concept

    1. Early Diabetes. Concept. Terminology

      • R. A. Camerini-Davalos
      Pages 1-6

    2. Early Stages of Diabetes: Definitions and Present Concepts

      • S. S. Fajans
      Pages 7-11

    3. Prediabetes in the Pima Indians

      • P. J. Savage, R. F. Hamman, P. H. Bennett
      Pages 13-19

    4. The Prognosis of Insulin Dependent Diabetes Mellitus and the Importance of Supervision

      • T. Deckert, M. Larsen
      Pages 21-27

    5. Discussion

      • Rafael A. Camerini-Davalos, Bernard Hanover
      Pages 29-32

  3. Genetic Influences on Islet Cell Function

    1. HLA System

      1. HLA and the Genetic Aspects of the Predisposition to Juvenile Diabetes Mellitus. A Follow-Up
        • P. Rubinstein, N. Suciu-Foca
        Pages 33-40
      2. HLA Studies in Diabetics
        • L. P. Ryder, M. Christy, J. Nerup, P. Platz, A. Svejgaard, M. Thomsen
        Pages 41-48
      3. Discussion
        • Rafael A. Camerini-Davalos, Bernard Hanover
        Pages 49-50

    2. Familial Patterns of Inheritance

      1. On the Genetic Heterogeneity of Juvenile Hyperglycemia
        • J. Barbosa, M. M. Chern
        Pages 51-57
      2. Familial Patterns of Inheritance of Diabetes Mellitus. Maturity-Onset Type Diabetes of Young People (MODY)
        • M. C. Cloutier, S. S. Fajans
        Pages 59-65
      3. Discussion
        • Rafael A. Camerini-Davalos, Bernard Hanover
        Pages 67-69

  4. Metabolic Aspects of Islet Cell Function

    1. Phosphate Translocations during Secretory Stimulation of Pancreatic Islets

      • N. Freinkel
      Pages 71-77

    2. The Role of Phosphoenolpyruvate and Lactate Production in Insulin Secretion

      • C. J. Hedeskov, K. Capito
      Pages 79-84

    3. Effects of Insulinotropic Agents on Cationic Fluxes in Islet Cells

      • W. J. Malaisse, A. Sener, A. Herchuelz
      Pages 85-96

    4. Glucose-Induced Changes of the Membrane Potential of Pancreatic B-Cells: Their Significance for the Regulation of Insulin Release

      • H. P. Meissner, M. Preissler
      Pages 97-107

    5. Discussion

      • Rafael A. Camerini-Davalos, Bernard Hanover
      Pages 109-114

  5. Abnormal Development of the Pancreas

    1. Effect of Maternal Carbohydrate Intolerance on the Development of the Autonomic Innervation of the Fetal Rat Pancreas

      • M. de Gasparo, P. de Herdt, J. J. Hoet
      Pages 115-122

    2. Discussion

      • Rafael A. Camerini-Davalos, Bernard Hanover
      Pages 123-123

  6. Environmental Factors Influencing Islet Cell Function

    1. Nutritional

      1. Suppression of Insulin Secretion by Protein Deprivation in Obesity
        • D. E. Schteingart, A. K. McKenzie, R. S. Victoria, H. S. Tsao
        Pages 125-132
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Keywords

About this book

To obey the precepts of therapeutic rationality, we should avoid treating the "effect" when there is a way to attack the cause. But what is the cause of diabetes? Diabetes is a molecular disease, that is, a disease in which important cellular components are seriously impaired. Eventually, the activities or the products arising from the impairment find expression in various ways, finally culminating in the abnormalities of diabetes. How early is early enough to attempt to delay this sequence of events? What will provide us with the basis to explore ways and means of halting the progression of the pathological process? What are the new approaches for the treatment of early diabetes? The Fourth International Symposium on Early Diabetes, sponsored by the Diabetes Center of the New York Medical College, held in Algarve, Portugal in November 1978, from which this book evolved, attempted to answer some of these questions. A list of the participants, including their affiliations, will be found preceding the index. Rafael A. Camerini-Davalos v Acknowledgments To our sponsors, U.S.V. Pharmaceutical Corp., Pfizer Pharmaceuticals, Ames Company, Hoechst, Frankfurt; supporters, Boehringer, Manheim, Laboratoires Servier, Nordisk Laboratory, The Upjohn Company, Eli Lilly and Company, F. Hoffman La Roche; and contributors, Bayer A. G. Leverkusen, McNeil, Novo Research Institute, ICI Belgium, Hope for Diabetics Foundation, New York, we express our appreciation for the financial support which made possible the Fourth International Symposium on Early Diabetes. THE ORGANIZING COMMITTEE Rafael A. Camerini-Davalos, M.D.

Editors and Affiliations

  • Diabetes Center, New York Medical College, New York, USA

    Rafael A. Camerini-Davalos, Bernard Hanover

Bibliographic Information

  • Book Title: Treatment of EARLY DIABETES

  • Editors: Rafael A. Camerini-Davalos, Bernard Hanover

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4615-9110-8

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1979

  • Softcover ISBN: 978-1-4615-9112-2Published: 27 December 2012

  • eBook ISBN: 978-1-4615-9110-8Published: 09 March 2013

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XVI, 532

  • Topics: Diabetes

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