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Tissue Hypoxia and Ischemia

  • Book
  • © 1977

Overview

Editors:
  1. Martin Reivich

    1. University of Pennsylvania, Philadelphia, USA

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  2. Ronald Coburn

    1. University of Pennsylvania, Philadelphia, USA

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  3. Sukhamay Lahiri

    1. University of Pennsylvania, Philadelphia, USA

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  4. Britton Chance

    1. University of Pennsylvania, Philadelphia, USA

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Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 78)

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Table of contents (32 chapters)

  1. Front Matter

    Pages i-xiv
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  2. The Biochemistry of Physiologic Oxygen Sensors

    1. Front Matter

      Pages 1-1
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    2. What is a Molecular Oxygen Sensor? What is a Transduction Process?

      • Frans F. Jobsis
      Pages 3-18

    3. The Oxygen Sensing Characteristics of Microsomal Enzymes

      • Ronald W. Estabrook, Jurgen Werringloer
      Pages 19-35

    4. Oxygen Sensing Heme Proteins: Monoxygenases, Myoglobin and Hemoglobin

      • I. C. Gunsalus, S. G. Sligar, T. Nordlund, H. Frauenfelder
      Pages 37-50

    5. Peroxisomal Enzymes and Oxygen Metabolism in Liver

      • Helmut Sies
      Pages 51-66

    6. Mitochondrial Production of Superoxide Radical and Hydrogen Peroxide

      • Alberto Boveris
      Pages 67-82

  3. Mechanism of Oxygen Sensing in Tissues

    1. Front Matter

      Pages 83-83
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    2. Chemoreception and Transduction on Neuronal Models

      • N. Chalazonitis
      Pages 85-100

    3. Oxygen Tension Sensors in Vascular Smooth Muscle*

      • R. F. Coburn
      Pages 101-115

    4. Comments on: Oxygen Tension Sensors in Vascular Smooth Muscle

      • Richard J. Paul
      Pages 117-122

    5. Mechanism of Oxygen Induced Contraction of Ductus Arteriosus

      • Fredric S. Fay, Pankajam Nair, William J. Whalen
      Pages 123-134

    6. Prostaglandins and the Control of Muscle Tone in the Ductus Arteriosus

      • F. Coceani, P. M. Olley, I. Bishai, E. Bodach, J. Heaton, M. Nashat et al.
      Pages 135-142

    7. The Sensing of Oxygen Tension in the Pulmonary Circulation

      • Alfred P. Fishman
      Pages 143-150

    8. The Sensing of Oxygen Tension in the Pulmonary Circulation — Discussion

      • Norman C. Staub
      Pages 151-161

    9. Circulatory Effects of Tissue Oxygen Tension Sensors

      • Robert M. Berne, Rafael Rubio
      Pages 163-174

    10. Bioassay and Pharmacologic Evaluation of the Adenosine Hypothesis

      • Francis J. Haddy
      Pages 175-182

  4. Mechanism of Oxygen Sensing in Tissues

    1. Front Matter

      Pages 183-183
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    2. Introductory Remarks: Oxygen Linked Response of Carotid Chemoreceptors

      • Sukhamay Lahiri
      Pages 185-202

    3. Convergence of Stimuli in Arterial Chemoreceptors

      • R. W. Torrance
      Pages 203-207
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Keywords

About this book

This monograph contains the proceedings of a symposium entitled, "Tissue Hypoxia and Ischemia," which was held at the Annenberg Center of the University of Pennsylvania on August 13 and 14, 1976. The symposium was jointly sponsored by the following groups at the University of Pennsylvania: the Respiratory Physiology Group of the Department of Physio­ logy, the Cardiopulmonary Section of the Department of Medicine, the Johnson Research Foundation, the Cerebrovascular Research Center of the Department of Neurology, the Head Injury Center of the Department of Neurosurgery, the. Institute for Environ­ mental Medicine, and the International Society on Oxygen Transport to Tissues. Its purpose was to promote an interdisciplinary discussion of oxygen sensors in various tissues and their mechanism of action as well as to examine the deleterious effects of hypoxia and ischemia with special reference to the brain. There were four sessions, one on the biochemistry of physi­ ologic oxygen sensors, two on the mechanism of oxygen sensing in tissues and one on the circulatory and metabolic aspects of cerebral hypoxia and ischemia.

Editors and Affiliations

  • University of Pennsylvania, Philadelphia, USA

    Martin Reivich, Ronald Coburn, Sukhamay Lahiri, Britton Chance

Bibliographic Information

  • Book Title: Tissue Hypoxia and Ischemia

  • Editors: Martin Reivich, Ronald Coburn, Sukhamay Lahiri, Britton Chance

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4615-9035-4

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1977

  • Softcover ISBN: 978-1-4615-9037-8Published: 27 December 2012

  • eBook ISBN: 978-1-4615-9035-4Published: 09 March 2013

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XIV, 385

  • Topics: Pathology

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